No Added Benefit with Adjuvant Chemoradiation in Gallbladder Cancer

Source link : https://www.newshealth.biz/health-news/no-added-benefit-with-adjuvant-chemoradiation-in-gallbladder-cancer/ In the first randomized controlled trial of its kind, researchers found that adding chemoradiation to adjuvant chemotherapy did not improve outcomes in patients with resected gallbladder cancer.  Results from the phase 3 ACCELERATE trial were presented at the Gastrointestinal Cancers Symposium (GICS) 2025 by Atul Sharma from the All India Institute […]

New Guidance Aims to Reduce Surgical Infections

Source link : https://www.newshealth.biz/health-news/new-guidance-aims-to-reduce-surgical-infections/ New guidelines from the American Society of Regional and Anesthesia (ASRA) Pain Medicine offer strategies for anesthesiologists and pain physicians to prevent infections that develop after surgery and other pain procedures. Surgical site infections (SSIs) — which by some estimates occur 500,000 times annually in the United States— increase hospital costs […]

Low-Dose Aspirin Cuts CRC Recurrence

Source link : https://www.newshealth.biz/health-news/low-dose-aspirin-cuts-crc-recurrence/ Low-dose aspirin reduced colorectal cancer (CRC) recurrence rates by more than half in patients with tumors harboring mutations in the PI3K signaling pathway, according to findings from the phase 3 ALASCCA trial. These results stress “the importance of upfront genomic testing” in patients with CRC, said Anna Martling, MD, PhD, from […]

Fatty Liver Screening Gaps Emerge in HIV Care Survey

Source link : https://www.newshealth.biz/health-news/fatty-liver-screening-gaps-emerge-in-hiv-care-survey/ TOPLINE: Two thirds of HIV care providers surveyed screen for nonalcoholic fatty liver disease (NAFLD) in patients with HIV (PWH). The main barriers to fatty liver screening are uncertainty about tests, insufficient diagnostic data, low priority, time constraints, and lack of referrals. METHODOLOGY: Guidance on NAFLD lacks specific considerations for PWH. […]

Women Underrepresented in Pharma-Sponsored IBD Presentations

Source link : https://www.newshealth.biz/health-news/women-underrepresented-in-pharma-sponsored-ibd-presentations/ A recent study found that despite their growing presence in inflammatory bowel disease (IBD) research, women investigators were inequitably represented at scientific presentations sponsored by the pharmaceutical industry. The study was published in Gastroenterology and also appeared concurrently inClinical Gastroenterology and Hepatology. Indeed, among gastrointestinal (GI) subspecialties, IBD was selected by 26.5% […]

Environment Drives Respiratory Health Disparities

Source link : https://www.newshealth.biz/health-news/environment-drives-respiratory-health-disparities/ In 2016, Brady Scott was in his parents’ home in Garrett, Kentucky, scrolling his Facebook feed when a post from a local newspaper caught his attention. “The article said that if you grew up in the region I grew up in, compared to the richer Central Kentucky region, the life expectancy […]

PCB Exposure Boosts Heart Disease Risk in T2D

Source link : https://www.newshealth.biz/health-news/pcb-exposure-boosts-heart-disease-risk-in-t2d/ TOPLINE: Elevated concentrations of serum polychlorinated biphenyls (PCBs) increase the risk for incident cardiovascular disease (CVD) by up to 30% among patients with type 2 diabetes (T2D). METHODOLOGY: Prior studies haven’t examined the impact of PCB exposure on patients with T2D, a group that may be more vulnerable to the heightened […]

Nicotinamide Riboside Relieves Airway Inflammation in COPD

Source link : https://www.newshealth.biz/health-news/nicotinamide-riboside-relieves-airway-inflammation-in-copd/ TOPLINE: Nicotinamide riboside (NR) supplementation may reduce airway inflammation and, thereby, lower the risk for exacerbation in patients with noneosinophilic chronic obstructive pulmonary disease (COPD) who smoked previously. METHODOLOGY: The anti-inflammatory effect of NR has been previously documented, and the current study investigated whether its supplementation could reduce airway inflammation in […]

Heart Disease Still Top Cause of Death

Source link : https://www.newshealth.biz/health-news/heart-disease-still-top-cause-of-death/ Heart disease remains the leading cause of death in the United States, fueled by ongoing increases in hypertension, obesity, and other major risk factors, according to the American Heart Association’s (AHA) 2025 Heart Disease and Stroke Statistics. Cardiovascular disease, which includes heart disease and stroke, claims more lives in the United […]

Goniotomy Effective for Childhood Uveitic Glaucoma

Source link : https://www.newshealth.biz/health-news/goniotomy-effective-for-childhood-uveitic-glaucoma/ TOPLINE: Goniotomy demonstrates effectiveness in managing intraocular pressure in childhood glaucoma secondary to chronic uveitis, with success rates maintained in the long term and no deterioration of inflammatory control immediately after the operation. METHODOLOGY: Researchers conducted a retrospective chart review to assess the long-term outcomes of goniotomy in children with glaucoma […]

How This Easy Change to BP Reading Can Reveal Hidden Risks

Source link : https://www.newshealth.biz/health-news/how-this-easy-change-to-bp-reading-can-reveal-hidden-risks/ TOPLINE: Having supine hypertension, regardless of seated or treated hypertension, is associated with an increased risk for adverse cardiovascular outcomes. Having supine hypertension was consistently associated with a greater risk for all cardiovascular outcomes than seated hypertension. METHODOLOGY: Researchers conducted a prospective analysis using data from the ARIC study to examine […]

Kids Who Watch Violence on TV May Become Aggressive Teens

Source link : https://www.newshealth.biz/health-news/kids-who-watch-violence-on-tv-may-become-aggressive-teens/ TOPLINE: In adolescent boys, exposure to violent television content during their preschool years is associated with increased levels of self-reported proactive aggression, physical aggression, and antisocial behavior by the age of 15 years; however, no such association has been observed in girls. METHODOLOGY: Researchers conducted a prospective longitudinal study to explore […]

Experts Warn Against Faricimab Rechallenge Post-Inflammation

Source link : https://www.newshealth.biz/health-news/experts-warn-against-faricimab-rechallenge-post-inflammation/ TOPLINE: Patients who develop mild intraocular inflammation after receiving faricimab may experience severe, irreversible vision loss when rechallenged with the drug. METHODOLOGY: Researchers reported on three patients (four eyes) treated at the University of Nebraska Medical Center, Omaha, Nebraska, who developed a mild anterior chamber reaction after receiving intravitreal faricimab. The […]

How Oncologists Can Recognize the Signs

Source link : https://www.newshealth.biz/health-news/how-oncologists-can-recognize-the-signs/ Last year, Eric Singhi, MD, a thoracic medical oncologist at MD Anderson Cancer Center in Houston, noticed a shift in his team. The small band of four clinicians, once motivated and enthusiastic, were now withdrawn and distant. “We had to take a break from clinic 1 day. We went out, got […]

Water Bead Ingestion Linked to Neurotoxicity

Source link : https://www.newshealth.biz/health-news/water-bead-ingestion-linked-to-neurotoxicity/ Water bead toys have the potential to cause not only intestinal obstruction in children who ingest them, but also neurotoxicity, a case study suggested. A 13-month-old female who was previously healthy presented to the emergency department with vomiting, lethargy, and weight loss over several weeks along with insomnia and facial dermatitis, […]

Should Pregnant Women Be Supplemented With Iodine?

Source link : https://www.newshealth.biz/health-news/should-pregnant-women-be-supplemented-with-iodine/ At the 2024 Journées Francophones de la Nutrition, held in Strasbourg from December 4 to 6, experts gathered to explore the important topic of contaminants and their effects on the thyroid. Among the key topics was the essential role of maternal thyroid hormones in fetal brain development. Maternal Thyroid Hormones Maternal […]

NICE asks GPs to identify potential gambling addicts

Source link : https://www.newshealth.biz/health-news/nice-asks-gps-to-identify-potential-gambling-addicts/ Annabel Rackham Health reporter, BBC News Getty Images Health watchdog NICE is asking doctors and other healthcare professionals to identify patients at risk of gambling addiction GPs and other healthcare professionals in England should help identify potential problem gambling, in the same way they look for alcohol and smoking addiction, new […]

Limbo of Cardiac Device Recalls Has Physicians Ready for Change

Source link : https://www.newshealth.biz/health-news/limbo-of-cardiac-device-recalls-has-physicians-ready-for-change/ LOS ANGELES — Clinicians working in advanced heart failure vented their frustrations about the shrinking number of device therapies left from round after round of FDA recalls. Could a changed regulatory climate under the Trump administration bring about more treatment options? The question came up during an audience Q&A session at […]

Novel Biomarkers Predict Pain Sensitivity

Source link : https://www.newshealth.biz/health-news/novel-biomarkers-predict-pain-sensitivity/ A biomarker signature using brain activity measurements predicted pain sensitivity. The signature combined sensorimotor peak alpha frequency and corticomotor excitability. The study involved 150 people who received nerve injections to test prolonged pain. A novel biomarker signature that assessed cortical activity predicted individual pain sensitivity, the PREDICT validation study showed. The […]

Here Are ‘Girl Dinners’ to Avoid to Limit Gout Risk

Source link : https://www.newshealth.biz/health-news/here-are-girl-dinners-to-avoid-to-limit-gout-risk/ Some dietary habits are worse than others when it comes to gout risk for women, a large study indicated. Data from the two iterations of the Nurses’ Health Study, in which more than 170,000 women were followed for more than two decades, indicated that diets scoring high on the Empirical Dietary […]

Two Non-Steroid Options for Childhood Nephrotic Syndrome Show Similar Benefits

Source link : https://www.newshealth.biz/health-news/two-non-steroid-options-for-childhood-nephrotic-syndrome-show-similar-benefits/ For children with nephrotic syndrome, there was no difference in time to relapse between two commonly used non-steroid immunosuppressive medications, according to an observational study that emulated a pragmatic trial. Among nearly 600 children, there was no significant difference in time to relapse between those taking a calcineurin inhibitor compared with […]

ctDNA Testing Shows Promise for Influencing Colorectal Cancer Treatment

Source link : https://www.newshealth.biz/health-news/ctdna-testing-shows-promise-for-influencing-colorectal-cancer-treatment/ SAN FRANCISCO — Circulating tumor DNA (ctDNA) measurements showed promise for identifying patients with early colorectal cancer (CRC) most likely to benefit from adjuvant therapy, analyses of two large clinical trials suggested. Patients who had positive ctDNA tests after surgery were almost twice as likely to be alive at 3 years […]

Gene Therapy Stabilizes Rare Chronic HPV Disease

Source link : https://www.newshealth.biz/health-news/gene-therapy-stabilizes-rare-chronic-hpv-disease/ For recurrent respiratory papillomatosis (RRP), novel gene therapy to jump-start immunity to the human papillomavirus (HPV) that causes it was safe and yielded complete response in many cases, a small pivotal trial showed. Fully 51% (18) of the 35 patients treated at the recommended phase II dose of PRGN-2012 had a […]

Norovirus Is Spreading Fast | MedPage Today

Source link : https://www.newshealth.biz/health-news/norovirus-is-spreading-fast-medpage-today/ Handy is a pediatric infectious diseases physician and an assistant professor of clinical pediatrics. It was 11 p.m. and I had just fallen asleep when I heard a cry from my 4-year-old son’s room. I headed downstairs to find a trail of vomit on the carpet and up the stairs, as […]

Vaccine Bills Stack Up in Statehouses Across the U.S.

Source link : https://www.newshealth.biz/health-news/vaccine-bills-stack-up-in-statehouses-across-the-u-s/ Vaccination bills are popping up in more than 15 states as lawmakers aim to potentially resurrect or create new religious exemptions from immunization mandates, establish state-level vaccine injury databases, or dictate what providers must tell patients about the shots. Many see a political opportunity to rewrite policies in their states after […]

Combination Slows Metastatic CRC Progression Better Than Single Immunotherapy

Source link : https://www.newshealth.biz/health-news/combination-slows-metastatic-crc-progression-better-than-single-immunotherapy/ SAN FRANCISCO — An immunotherapy combination for advanced, highly mutated colorectal cancer (CRC) significantly slowed disease progression versus a single drug, according to a randomized study. Median progression-free survival (PFS) had yet to be reached with nivolumab (Opdivo) plus ipilimumab (Yervoy) after 47 months of follow-up as compared with a median […]

The $5 Trillion Question | MedPage Today

Source link : https://www.newshealth.biz/health-news/the-5-trillion-question-medpage-today/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. What could we do with $5 trillion? Apparently, we do a lot, and yet sometimes it seems like it’s just […]

COVID, Flu, and RSV: Which Virus Has the Worst Outcomes?

Source link : https://www.newshealth.biz/health-news/covid-flu-and-rsv-which-virus-has-the-worst-outcomes/ SARS-CoV-2 infection was associated with more severe disease outcomes than influenza or respiratory syncytial virus (RSV) during the 2022-2023 respiratory illness season, while differences were less striking during the 2023-2024 season, according to a retrospective cohort study of veterans. The 30-day risk of death during the 2022-2023 season was 1.0% for […]

Health Groups Prepare for the Unthinkable: Working With RFK Jr.

Source link : https://www.newshealth.biz/health-news/health-groups-prepare-for-the-unthinkable-working-with-rfk-jr/ When President Trump tapped Robert F. Kennedy Jr. to become the nation’s top health official, his administration inherited a sprawling list of ideas to “Make America Healthy Again,” from banning TV drug advertisements to dropping restrictions on raw milk. While those unorthodox proposals — and Kennedy’s discredited views on vaccines — […]

Real-World Practice Upholds Lobectomy for Early-Stage Lung Cancer

Source link : https://www.newshealth.biz/health-news/real-world-practice-upholds-lobectomy-for-early-stage-lung-cancer/ LOS ANGELES — Surgeries to remove small tumors in stage IA non-small cell lung cancer (NSCLC) were associated with varying odds of long-term survival depending on the amount of lung removed, based on real-world data collected from across the country. In routine practice, unadjusted 10-year overall survival (OS) for lobectomy reached 44.8%, […]

HPV Follow-up Testing Falls Short

Source link : https://www.newshealth.biz/health-news/hpv-follow-up-testing-falls-short/ TOPLINE:  Fewer than half of patients testing positive for HPV received recommended annual follow-up testing, a new cohort study found. Healthcare systems should track surveillance rates and research interventions to improve follow-up care, the authors concluded. METHODOLOGY:   Healthcare systems are shifting toward primary HPV screening and co-testing, making HPV-positive results […]

CIA Backs COVID ‘Lab Leak’; Trump Fires Health Watchdog; PEPFAR Funding Freeze

Source link : https://www.newshealth.biz/health-news/cia-backs-covid-lab-leak-trump-fires-health-watchdog-pepfar-funding-freeze/ Note that some links may require registration or subscription. The CIA now believes that COVID-19 most likely originated from a lab, but cited “low confidence” in its new assessment. (AP) A Department of Labor investigation on insurance coverage of mental health care revealed broad noncompliance and an “alarming” rate of ghost […]

Tips to Help Your Patients Manage Their Drug Costs

Source link : https://www.newshealth.biz/health-news/tips-to-help-your-patients-manage-their-drug-costs/ The high cost of many medicines in the United States may make it easier for clinicians to start necessary conversations about whether patients will be able to afford to fill the prescriptions written for them. In the past, it was a more sensitive topic as patients could be reluctant to discuss […]

Are there Benefits to ‘Yo-Yo Dieting?’

Source link : https://www.newshealth.biz/health-news/are-there-benefits-to-yo-yo-dieting/ Weight loss is crucial for improving health and decreasing disease risk in those with overweight and obesity. Unfortunately, many individuals who lose weight through lifestyle interventions (nutrition and exercise) and bariatric surgery don’t sustain the loss, and those taking anti-obesity medications typically regain the weight when they discontinue the drugs. Repeated […]

Should Biomarkers (and Pharma) Drive Alzheimer’s Diagnosis?

Source link : https://www.newshealth.biz/health-news/should-biomarkers-and-pharma-drive-alzheimers-diagnosis/ Many Alzheimer’s experts were dismayed — but not surprised — when the Alzheimer’s Association stated that the disease could be diagnosed on the basis of pathology using biomarkers, rather than symptoms. The June 2024“Revised Criteria for Diagnosis and Staging of Alzheimer’s Disease” evolved from a 2018 “research framework” paper that proposed […]

Bariatric Surgery in MASH Patients Improved Long-Term Outcomes

Source link : https://www.newshealth.biz/health-news/bariatric-surgery-in-mash-patients-improved-long-term-outcomes/ Bariatric surgery significantly reduced long-term risk for decompensation and adverse outcomes in patients with obesity and compensated metabolic dysfunction-associated steatohepatitis (MASH)-related cirrhosis, according to an observational study. In 62 patients who underwent bariatric surgery, the 15-year cumulative incidence of major adverse liver outcomes was 21% compared with 46% in control patients […]

Immunotherapy + CRT Boosts Response in Esophageal Cancer

Source link : https://www.newshealth.biz/health-news/immunotherapy-crt-boosts-response-in-esophageal-cancer/ A novel treatment approach combining neoadjuvant immunotherapy with chemoradiation showed promising results in patients with locally advanced esophageal squamous cell carcinoma (ESCC), according to preliminary findings from the phase 3 SCIENCE trial. Lead investigator Xuefeng Leng, MD, PhD, of Sichuan Cancer Hospital, Chengdu, China, presented these results at the ASCO Gastrointestinal […]

Drug Combo for Common Neuroendocrine Tumor: A New Standard?

Source link : https://www.newshealth.biz/health-news/drug-combo-for-common-neuroendocrine-tumor-a-new-standard/ Adding the somatostatin analog lanreotide to the mTOR inhibitor everolimus significantly prolonged progression-free survival in patients with unresectable or recurrent gastroenteropancreatic neuroendocrine tumors compared with everolimus alone.  This combination has “the potential to become a new standard first-line treatment” for well-differentiated grade 1/2 gastroenteropancreatic neuroendocrine tumors with poor prognostic factors, said […]

Thyroid Cancer Detections Due to More Screenings With GLP-1s

Source link : https://www.newshealth.biz/health-news/thyroid-cancer-detections-due-to-more-screenings-with-glp-1s/ New research, with the caveat of a relatively short follow-up, adds to encouraging data showing an overall low risk of the development of thyroid cancer associated with glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment. However, a notably increased rate of thyroid cancer detections limited only to the first year after […]

AI LLMs Not So Great in Answering Rheumatology Questions

Source link : https://www.newshealth.biz/health-news/ai-llms-not-so-great-in-answering-rheumatology-questions/ TOPLINE: Large language models (LLMs) perform differently in answering rheumatology questions, with ChatGPT-4 demonstrating higher accuracy and quality than Gemini Advanced and Claude 3 Opus. However, more than 70% of incorrect answers by all three had the potential to cause harm.  METHODOLOGY: Researchers evaluated the accuracy, quality, and safety of three […]

EU Acts to Boost Cybersecurity in Hospitals

Source link : https://www.newshealth.biz/health-news/eu-acts-to-boost-cybersecurity-in-hospitals/ The European Commission has introduced an action plan to strengthen the cybersecurity of hospitals and healthcare providers across the European Union (EU). The initiative includes creating a pan-European Cybersecurity Support Centre, managed by the European Network and Information Security Agency, to address the rising number of cyber threats targeting healthcare institutions. […]

Early Signs of Huntington’s Detectable Long Before Symptoms

Source link : https://www.newshealth.biz/health-news/early-signs-of-huntingtons-detectable-long-before-symptoms/ Subtle signs of neurodegeneration can be detected in blood, cerebrospinal fluid (CSF), and through neuroimaging, up to two decades before motor symptoms in Huntington’s disease (HD) present, new research showed. Investigators believe these early biomarkers could pave the way for novel interventions that could improve outcomes for individuals at risk for […]

Frequent Polyp Diagnoses in Relatives Linked to CRC Risk

Source link : https://www.newshealth.biz/health-news/frequent-polyp-diagnoses-in-relatives-linked-to-crc-risk/ TOPLINE: Frequent colorectal polyp diagnoses in first- and second-degree relatives are associated with an increased risk for colorectal cancer (CRC), especially early-onset CRC. METHODOLOGY: Researchers evaluated the association between the frequency of colorectal polyp diagnoses in relatives and the risk for overall and early-onset CRC using data from four Swedish family […]

Pioglitazone May Reduce Skin Ulcer Risk in Rare Disorder

Source link : https://www.newshealth.biz/health-news/pioglitazone-may-reduce-skin-ulcer-risk-in-rare-disorder/ TOPLINE: A Japanese study suggests that age and higher blood pressure significantly increase the risk for skin ulcers in patients with Werner syndrome (WS), while treatment with pioglitazone may offer protection. METHODOLOGY: Researchers analyzed data from 51 patients with WS enrolled in the Japanese Werner Syndrome Registry between 2016 and 2022. […]

Geriatrics-Focused Systems Offer Limited Benefits to Seniors

Source link : https://www.newshealth.biz/health-news/geriatrics-focused-systems-offer-limited-benefits-to-seniors/ TOPLINE: Compared with traditional primary care systems, geriatrics-focused primary care systems provide better quality of care but fail to improve health and wellness outcomes in older veterans with multiple chronic conditions and social issues. METHODOLOGY: Researchers compared the effects of geriatrics-focused primary care systems with those of traditional primary care systems […]

Covid smell loss eased by injecting blood cells into the nose

Source link : https://www.newshealth.biz/health-news/covid-smell-loss-eased-by-injecting-blood-cells-into-the-nose/ Transmission electron micrograph of SARS-CoV-2 virus particles (gold) within a nasal cell BSIP SA/Alamy People who had lost their sense of smell after catching covid-19 partly regained it following the injection of blood cells called platelets into their noses, which could help to improve their quality of life. Since the beginning […]

Drug Duo Enhances Myeloma Outcomes

Source link : https://www.newshealth.biz/health-news/drug-duo-enhances-myeloma-outcomes/ TOPLINE: Adding daratumumab to lenalidomide maintenance therapy after transplant in patients with multiple myeloma triples the minimal residual disease (MRD)–negative conversion rate to 50.5% vs 18.8% with lenalidomide alone. The combination therapy reduces progression risk by 47% and achieves estimated 30-month progression-free survival (PFS) rates of 82.7% vs 66.4% for lenalidomide […]

Triple Therapy in Metastatic CRC With BRAF Mutations: The New Standard of Care?

Source link : https://www.newshealth.biz/health-news/triple-therapy-in-metastatic-crc-with-braf-mutations-the-new-standard-of-care/ SAN FRANCISCO — First-line treatment with targeted therapies plus chemotherapy offered overall response benefits in BRAF V600E-mutant metastatic colorectal cancer (mCRC), according to the BREAKWATER trial. The study looked at encorafenib (Braftovi) and cetuximab (Erbitux) plus mFOLFOX6 chemotherapy (EC-FOLFOX6) versus standard of care (SOC), and demonstrated a 60.9% overall response rate […]

60 or Younger? A ‘Wake Up Call’ for Mechanical Aortic Valve Replacement

Source link : https://www.newshealth.biz/health-news/60-or-younger-a-wake-up-call-for-mechanical-aortic-valve-replacement/ LOS ANGELES — Survival outcomes favored mechanical valves for isolated surgical aortic valve replacement (SAVR) for people until age 60, after which a tissue valve may start to have an advantage, according to a large registry analysis. Using the STS Adult Cardiac Surgery Database, researchers found that comparisons of adjusted mortality […]

‘It’s a Disservice to Dr. Fauci’: What We Heard This Week

Source link : https://www.newshealth.biz/health-news/its-a-disservice-to-dr-fauci-what-we-heard-this-week/ “It’s a disservice to Dr. Fauci that they felt this was necessary.” — Georges Benjamin, MD, executive director of the American Public Health Association, discussing former President Joe Biden’s decision to preemptively pardon Anthony Fauci, MD. “Not all depressive symptoms are created equal.” — Jennifer Gatchel, MD, PhD, of Massachusetts General […]

A Broken Clock: RFK Jr. Gets Two Things Right on Health

Source link : https://www.newshealth.biz/health-news/a-broken-clock-rfk-jr-gets-two-things-right-on-health/ N. Adam Brown is a practicing emergency physician, entrepreneur, and healthcare executive. He is the founder of ABIG Health, a healthcare growth strategy firm, and a professor at the University of North Carolina’s Kenan-Flagler Business School. Follow President Donald Trump is back in the White House, but his cabinet is still […]

Heart Surgeons Wary of Being ‘Left Behind’ in Tricuspid Innovation

Source link : https://www.newshealth.biz/health-news/heart-surgeons-wary-of-being-left-behind-in-tricuspid-innovation/ LOS ANGELES — Cardiac surgeons were urged to readjust their attitudes toward the tricuspid valve if they want to keep some footing in a rapidly evolving field dominated by transcatheter innovations. At the Society of Thoracic Surgeons (STS) annual meeting, it was standing room only at a session dedicated to why […]

Immunotherapy-TACE Regimen Boosts PFS in Unresectable Liver Cancer

Source link : https://www.newshealth.biz/health-news/immunotherapy-tace-regimen-boosts-pfs-in-unresectable-liver-cancer/ SAN FRANCISCO — Adding camrelizumab and rivoceranib to transarterial chemoembolization (TACE) significantly prolonged progression-free survival (PFS) in patients with unresectable hepatocellular carcinoma (HCC), according to results from the CARES-005 study. At a median follow-up of 13.6 months, the median PFS was 10.8 months with TACE plus camrelizumab and rivoceranib (TACE-CR) versus […]

Practice-Changing Win for Aspirin in Colorectal Cancer

Source link : https://www.newshealth.biz/health-news/practice-changing-win-for-aspirin-in-colorectal-cancer/ SAN FRANCISCO — In an era dominated by pricey, high-tech drugs, the humble aspirin had a practice-changing impact on colorectal cancer (CRC) recurrence, according to a randomized study reported here. Patients with treated, PI3K-mutated early CRC had a 50-60% lower risk of recurrence at 3 years if they received 160 mg […]

Inhaled Pulmonary Vasodilators for Surgery: Choice Still Up for Debate

Source link : https://www.newshealth.biz/health-news/inhaled-pulmonary-vasodilators-for-surgery-choice-still-up-for-debate/ LOS ANGELES — For surgeons already split on their preference of inhaled pulmonary vasodilator to prevent postoperative right ventricular (RV) failure, a shifting market is not helping decision-making, as highlighted by a debate here at the Society of Thoracic Surgeons (STS) annual meeting. Between nitric oxide and epoprostenol, “it’s hard to […]

Geriatric Assessment, QoL Correlate With OS in Older Patients with Pancreatic Cancer

Source link : https://www.newshealth.biz/health-news/geriatric-assessment-qol-correlate-with-os-in-older-patients-with-pancreatic-cancer/ SAN FRANCISCO — Older patients’ survival in metastatic pancreatic cancer had a significant association with baseline vulnerabilities and quality-of-life (QoL) factors, beyond performance status, data from a randomized study showed. Baseline nutrition status had the strongest association with overall survival (OS), showing a 17% decrease in the survival hazard with each […]

What Publication Was Halted by Trump’s Gag Order?

Source link : https://www.newshealth.biz/health-news/what-publication-was-halted-by-trumps-gag-order/ (MedPage Today) — You passed medical training, now see if you can pass our weekly quiz Source link : https://www.medpagetoday.com/quizzes/news-quiz/113931 Author : Publish date : 2025-01-25 22:00:00 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date : 2025-01-25 22:00:00 Copyright for syndicated content belongs to […]

Trends in Aspirin Use; Top Treatments for Localized Esophageal Cancer

Source link : https://www.newshealth.biz/health-news/trends-in-aspirin-use-top-treatments-for-localized-esophageal-cancer/ TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center in El Paso, look at the top medical stories of the week. This week’s topics include […]

How Online Reviews Fail Physicians

Source link : https://www.newshealth.biz/health-news/how-online-reviews-fail-physicians/ The rise of online reviews has transformed how we evaluate everything from restaurants to service providers. While these systems are convenient and empowering for consumers, their application in healthcare raises unique challenges — particularly for physicians. Reviews on search engines — like Google, for example — appear to have unintentionally created […]

Big Brother’s Aisleyne Horgan-Wallace ‘Nearly Died’ From Fake Ozempic

Source link : https://www.newshealth.biz/health-news/big-brothers-aisleyne-horgan-wallace-nearly-died-from-fake-ozempic/ Share on Pinterest Ricky Vigil M/Justin E Palmer/GC Images/Getty ImagesCounterfeit versions of Ozempic have become a growing concern. Ricky Vigil M/Justin E Palmer/GC Images/Getty Images Former Big Brother UK star Aisleyne Horgan-Wallace said she “thought she was going to die” after taking suspected fake Ozempic. Horgan-Wallace said she experienced severe vomiting, […]

What to Know About President Trump’s Order Targeting Transgender Rights

Source link : https://www.newshealth.biz/health-news/what-to-know-about-president-trumps-order-targeting-transgender-rights/ An executive order President Trump signed on his first day back in office offers a new federal government definition of the sexes that could have a major impact on transgender people nationwide. The order calls for the federal government to define sex as only male or female and for that to […]

Read Anthony Fauci’s Pardon Here

Source link : https://www.newshealth.biz/health-news/read-anthony-faucis-pardon-here/ Executive Grant of Clemency Joseph R. Biden, Jr. President of the United States of America To all to whom these presents shall come, greeting: Be it known, that this day, I, Joseph R. Biden, Jr., President of the United States, pursuant to my powers under Article II, Section 2, Clause 1, […]

Hospitals awaiting rebuilds face sewage leaks and delayed ops

Source link : https://www.newshealth.biz/health-news/hospitals-awaiting-rebuilds-face-sewage-leaks-and-delayed-ops/ BBC Flooding in the basement is one of many incidents at the Princess Alexandra Hospital The Princess Alexandra Hospital in Essex has been plagued by problems with its ageing buildings and equipment in recent years. It has regular difficulties with floods and sewage leaks across its site, which dates back to […]

Therapeutic HPV Vaccine Effective in Reducing Precancerous Cervical Lesions

Source link : https://www.newshealth.biz/health-news/therapeutic-hpv-vaccine-effective-in-reducing-precancerous-cervical-lesions/ An investigational therapeutic vaccine showed clinical effectiveness in patients with human papillomavirus (HPV)16-positive cervical intraepithelial neoplasia grade 3 (CIN3), according to results from a small phase II study. Treatment with Vvax001 — comprised of replication-deficient recombinant Semliki Forest virus particles encoding a fusion protein of the oncogenic proteins and tumor-specific antigens […]

Neoadjuvant Chemoradiation Plus Immunotherapy Boosts Responses in Esophageal Cancer

Source link : https://www.newshealth.biz/health-news/neoadjuvant-chemoradiation-plus-immunotherapy-boosts-responses-in-esophageal-cancer/ SAN FRANCISCO — Neoadjuvant chemoradiotherapy with or without the investigational PD-1 inhibitor sintilimab significantly increased pathological complete response (pCR) rates compared with neoadjuvant chemotherapy plus sintilimab in patients with locally advanced esophageal squamous cell carcinoma (ESCC), preliminary results from a randomized phase III trial in China showed. Among 146 patients, the […]

Emergency Contraceptive Pill Could Work in Place of Mifepristone, Study Suggests

Source link : https://www.newshealth.biz/health-news/emergency-contraceptive-pill-could-work-in-place-of-mifepristone-study-suggests/ Ulipristal acetate, a selective progesterone receptor modulator, combined with misoprostol resulted in pregnancy termination among nearly all participants in a small proof-of-concept study. Of the 133 participants, 129 (97%) who received oral ulipristal acetate 60 mg followed 24 hours later by buccal misoprostol 800 μg had their pregnancy terminated, reported Manuel […]

Trump Administration Withdraws Plan to Ban Menthol Cigarettes

Source link : https://www.newshealth.biz/health-news/trump-administration-withdraws-plan-to-ban-menthol-cigarettes/ The Trump administration has withdrawn a proposed rule from FDA that would have banned menthol cigarettes. The proposed rule, which had been in the works since mid-2022, was listed as “Withdrawn” as of January 21 on an Office of Management and Budget (OMB) webpage. Approval by the OMB is one of […]

Mothers With MS Have Higher Incidence of Mental Illness

Source link : https://www.newshealth.biz/health-news/mothers-with-ms-have-higher-incidence-of-mental-illness/ Mothers with multiple sclerosis (MS) had a higher risk of peripartum mental illness compared with mothers without MS. Incident mental illness affected 8.4% of women with MS prenatally and 14.2% in the first postpartum year. Mental illness prevalence was 42% during pregnancy and 50.3% in the first postpartum year. Mothers with […]

PBM Regulation Bill a Good Possibility This Year, House Staffer Says

Source link : https://www.newshealth.biz/health-news/pbm-regulation-bill-a-good-possibility-this-year-house-staffer-says/ Legislation providing more scrutiny for pharmacy benefit managers (PBMs) that failed to make it through Congress in the waning days of 2024 seems to still be viable for passage this year, according to a House staff member. “I think there’s plenty of political will there; that’s what I’ve seen from members,” […]

Faricimab Again Linked to Rare but Severe Eye Adverse Effects

Source link : https://www.newshealth.biz/health-news/faricimab-again-linked-to-rare-but-severe-eye-adverse-effects/ Three patients developed occlusive retinal vasculitis following rechallenge with faricimab (Vabysmo) after initially developing mild intraocular inflammation for the treatment of neovascular age-related macular degeneration (nAMD) or diabetic macular edema, according to a retrospective case series. At a single academic tertiary referral center, mild intraocular inflammation developed in four eyes following […]

Trump Ends Fauci’s Security Detail

Source link : https://www.newshealth.biz/health-news/trump-ends-faucis-security-detail/ President Trump has ended the federal security detail for Anthony Fauci, MD, the infectious disease expert who advised him on the COVID-19 pandemic, a person familiar with the matter said Friday. Fauci is the latest in a string of former Trump aides-turned-critics to see their federal protection canceled despite ongoing threats […]

Autism Prevalence Is Climbing, but It’s Not Due to Vaccines

Source link : https://www.newshealth.biz/health-news/autism-prevalence-is-climbing-but-its-not-due-to-vaccines/ President Trump has said that Robert F. Kennedy Jr., his nominee to run HHS, would investigate why autism spectrum disorder (ASD) diagnoses are rising. Since at least 2014, Trump has floated a theory that vaccines are behind the rise, but no evidence indicates this is true. “There have been extensive studies […]

High Success Rate With Conversion Therapy for Unresectable Gastroesophageal Cancer

Source link : https://www.newshealth.biz/health-news/high-success-rate-with-conversion-therapy-for-unresectable-gastroesophageal-cancer/ SAN FRANCISCO — Three-fourths of patients with unresectable gastroesophageal cancer converted to resectable and had clear margins after treatment with a chemoimmunotherapy combination, a small Chinese study showed. Results showed that 39 of 52 patients had clear margins (R0) after surgery, following treatment with the PD-1 antibody camrelizumab and chemotherapy. Nearly […]

NIH Meeting Cancellations Could Impact Cancer Research

Source link : https://www.newshealth.biz/health-news/nih-meeting-cancellations-could-impact-cancer-research/ This week, the Trump administration imposed a range of restrictions that impact the National Institutes of Health (NIH). These include sudden meeting cancellations, such as expert panels that review grant proposals, as well as a broader pause on external communications at the US Department of Health and Human Services (HHS), HHS […]

Importance of Personalized Photoprotection Highlighted

Source link : https://www.newshealth.biz/health-news/importance-of-personalized-photoprotection-highlighted/ With the wide variety of sunscreen options available for photoprotection in the United States, one might expect dermatologists to tailor their recommendations based on a patient’s skin type — but that’s not always the case. According to a 2021 survey of 77 dermatology trainees and dermatology faculty across all hospitals affiliated […]

Trump Pardons Anti-Abortion Activists Who Blockaded Clinic Entrances

Source link : https://www.newshealth.biz/health-news/trump-pardons-anti-abortion-activists-who-blockaded-clinic-entrances/ President Donald Trump announced Thursday he would pardon anti-abortion activists convicted of blockading abortion clinic entrances. Trump called it “a great honor to sign this.” “They should not have been prosecuted,” he said as he signed pardons for “peaceful pro-life protesters.” The people pardoned were involved in the October 2020 invasion […]

FDA OKs Esketamine Nasal Spray Monotherapy for Depression

Source link : https://www.newshealth.biz/health-news/fda-oks-esketamine-nasal-spray-monotherapy-for-depression/ The US Food and Drug Administration (FDA) has approved a supplemental new drug application allowing esketamine nasal spray (Spravato; Johnson & Johnson) to be used as a standalone treatment in adults with major depressive disorder who have not responded adequately to at least two oral antidepressants.  The FDA first approved esketamine […]

Fake Cancer Drugs; Let’s Talk About Sex; Reducing Cancer-Related Fatigue

Source link : https://www.newshealth.biz/health-news/fake-cancer-drugs-lets-talk-about-sex-reducing-cancer-related-fatigue/ Beware of fake cancer drugs that have found their way into the booming online business of counterfeit prescription medications. (Roswell Park Comprehensive Cancer Center) Cecile Richards, 67, former president of Planned Parenthood and long-time abortion-rights activist, died of brain cancer earlier this week. (The Guardian) Clinicians often do not discuss sex […]

Trump’s Gain-of-Function Plan; Is Anyone in Charge at CDC? Andie MacDowell’s Dx

Source link : https://www.newshealth.biz/health-news/trumps-gain-of-function-plan-is-anyone-in-charge-at-cdc-andie-macdowells-dx/ Note that some links may require registration or subscription. The Trump administration is crafting an executive order that would halt federal funding for gain-of-function research. (Wall Street Journal via MSN) Meanwhile, Trump is cracking down on telework with a return-to-work order and MedPage Today plans to write about federal workers at […]

How Disaster Planning Can Protect Your Practice From Financial Ruin

Source link : https://www.newshealth.biz/health-news/how-disaster-planning-can-protect-your-practice-from-financial-ruin/ On August 29, 2005, Hurricane Katrina invaded the Gulf Coast, with New Orleans at the center of the storm. Not long after, the city was 80% underwater. There was a mandatory evacuation, and everyone — doctors and hospital staff included — was forced to leave. We were not able to return […]

A Guide for Discussing GLP-1s as Obesity Treatments

Source link : https://www.newshealth.biz/health-news/a-guide-for-discussing-glp-1s-as-obesity-treatments/ The arrival of drugs that mimic the gut hormone glucagon-like peptide 1 (GLP-1) has revolutionized the treatment of overweight and obesity, offering a biologic intervention that targets the root neurohormonal and genetic causes of these chronic conditions. However, the journey to successful treatment can be fraught with challenges, including patient hesitancies […]

Simple Retinal Scan May Help Predict Stroke Risk

Source link : https://www.newshealth.biz/health-news/simple-retinal-scan-may-help-predict-stroke-risk/ Researchers have identified novel retinal vascular signatures that are significantly associated with the risk for a first stroke. When combined with age and sex, these retinal “fingerprints” predicted stroke risk as well as established traditional risk factors.  The fingerprint, which consists of 29 retinal parameters that measure retinal health, can be […]

Boosting Lignan Intake in T2D May Lower Mortality Risk

Source link : https://www.newshealth.biz/health-news/boosting-lignan-intake-in-t2d-may-lower-mortality-risk/ TOPLINE: Higher intake of lignans — a group of plant-based antioxidants abundant in flaxseeds, whole grains, coffee, and some fruits and vegetables — is associated with a reduced risk for all-cause mortality and lower cardiovascular disease (CVD) mortality in individuals diagnosed with type 2 diabetes (T2D), especially in non-White individuals. METHODOLOGY: […]

Competition Remains Elusive in Private Insurance Market

Source link : https://www.newshealth.biz/health-news/competition-remains-elusive-in-private-insurance-market/ Competition among US private insurance companies has generally declined since 2011 in large-group, small-group, and individual markets, a government report found. However, the trend has slowed or even reversed in some states over the past few years. Meanwhile, an American Medical Association (AMA) analysis warns that “the vast majority of health […]

Which Influenza Antivirals Are Actually Helping Patients?

Source link : https://www.newshealth.biz/health-news/which-influenza-antivirals-are-actually-helping-patients/ Antivirals recommended by the Centers for Disease Control and Prevention (CDC) for treating influenza showed little benefit for nonsevere cases in a systematic review and meta-analysis published in JAMA Internal Medicine. Oseltamivir (Tamiflu) and zanamivir (Relenza) had little to no effect on mortality, hospitalization rates, or symptom duration. Peramivir (Rapivab) had […]

Managing GI and Liver Conditions During Pregnancy

Source link : https://www.newshealth.biz/health-news/managing-gi-and-liver-conditions-during-pregnancy/ Clinicians should be aware of how to manage certain gastrointestinal (GI) and liver conditions associated with pregnancy, such as hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, and acute fatty liver of pregnancy, according to a clinical practice update (CPU) from the American Gastroenterological Association. Notably, procedures, medications, or other interventions intended to […]

European Medical Groups Call for Action on Workforce Crisis

Source link : https://www.newshealth.biz/health-news/european-medical-groups-call-for-action-on-workforce-crisis/ The European Union of Medical Specialists and seven other European medical organizations have published a joint policy paper to address Europe’s ongoing health workforce crisis.  The World Health Organization has estimated that Europe will have a shortage of 600,000 doctors, 2.3 million nurses, and 1.1 million social care staff and assistants […]

Steroids in Pregnancy May Heighten Autism, ADHD Risk in Child

Source link : https://www.newshealth.biz/health-news/steroids-in-pregnancy-may-heighten-autism-adhd-risk-in-child/ Children exposed to glucocorticoids prenatally may have an increased risk of developing autism, attention-deficit/hyperactivity disorder (ADHD), and other mood-related conditions, according to a study published in JAMA Network Open. Researchers from Aarhus University in Aarhus, Denmark, analyzed data from over 1 million births in Denmark from 1999 to 2016. Previous studies linking […]

A ‘Nagging Gap’: Screening Men for Osteoporosis

Source link : https://www.newshealth.biz/health-news/a-nagging-gap-screening-men-for-osteoporosis/ Earlier this month, the US Preventive Services Task Force (USPSTF) released updated screening recommendations for osteoporosis. The task force reaffirmed their 2018 recommendations that all women aged 65 years or older and postmenopausal women younger than 65 years at increased risk for osteoporotic fracture should be screened. Notably, there were no […]

Stop DMT in Stable Multiple Sclerosis: Yes or No?

Source link : https://www.newshealth.biz/health-news/stop-dmt-in-stable-multiple-sclerosis-yes-or-no/ A significant portion of patients with multiple sclerosis (MS) can achieve a stable disease state when treated with modern disease-modifying therapy (DMT), especially when started early in the disease course, begging the question — can these medications be stopped? Research into the safety of stopping DMT in patients with stable MS […]

Patients, Outcomes Similar at Academic, Community Hospitals

Source link : https://www.newshealth.biz/health-news/patients-outcomes-similar-at-academic-community-hospitals/ Patient demographics and outcomes are similar at academic and community hospitals in Ontario, new research indicates. A retrospective cohort study included all adult general medicine patients admitted to or discharged from 28 hospitals in Ontario, Canada, between April 2015 and December 2021.  Researchers compared demographic and clinical characteristics (including age, sex, […]

Loneliness During Adolescence May Affect Health in Adulthood

Source link : https://www.newshealth.biz/health-news/loneliness-during-adolescence-may-affect-health-in-adulthood/ TOPLINE: Increased loneliness during adolescence is associated with various health and well-being outcomes, including an increased risk for asthma and depression, in adulthood. METHODOLOGY: Researchers conducted a longitudinal study to examine the association between increased loneliness over 1 year during adolescence and its subsequent health and well-being outcomes in adulthood. They […]

Home Cannabis Smoke Leaves Traces in Children’s Urine Tests

Source link : https://www.newshealth.biz/health-news/home-cannabis-smoke-leaves-traces-in-childrens-urine-tests/ TOPLINE: Children living in households with reported in-home cannabis smoking show five times higher odds of having detectable tetrahydrocannabinol (THC) equivalents in their urine than those without exposure. Among 275 children studied, 27.3% had detectable urinary cannabinoids. METHODOLOGY: A cross-sectional analysis included 275 children (mean age, 3.6 years) from San Diego […]

Birch Bark Gel Shows Sustained Benefits for EB

Source link : https://www.newshealth.biz/health-news/birch-bark-gel-shows-sustained-benefits-for-eb/ TOPLINE: Long-term treatment with Oleogel-S10 (birch bark extract, Filsuvez) gel significantly reduced wound burden and disease activity in individuals with epidermolysis bullosa (EB), with a high adherence rate and a manageable safety profile over 24 months. METHODOLOGY: In the phase 3 randomized EASE trial, patients with dystrophic and junctional EB (DEB […]

Dapagliflozin and Calorie Restriction Achieves T2D Remission

Source link : https://www.newshealth.biz/health-news/dapagliflozin-and-calorie-restriction-achieves-t2d-remission/ TOPLINE: Combining dapagliflozin with calorie restriction achieved a greater type 2 diabetes (T2D) remission rate and significant changes in body fat and metabolic risk factors than calorie restriction alone. METHODOLOGY: Researchers conducted a multicenter, double blind, randomized, placebo-controlled trial at 16 centers in mainland China from June 2020 through January 2023. […]

More Research Backs Migraine Meds as Heart Safe

Source link : https://www.newshealth.biz/health-news/more-research-backs-migraine-meds-as-heart-safe/ TOPLINE: The use of anti–calcitonin gene-related peptide monoclonal antibodies (anti-CGRP mAbs) was not linked to increased risk for a cardiovascular disease (CVD) event in a cohort study of older adults with migraine. METHODOLOGY: Researchers conducted a retrospective, sequential cohort study from 2018 to 2020, analyzing data from Medicare beneficiaries aged 18 […]

Can Breast Cancer Screening Be Better Tailored to Risk?

Source link : https://www.newshealth.biz/health-news/can-breast-cancer-screening-be-better-tailored-to-risk/ SAN ANTONIO — Can breast cancer screening be better tailored to a person’s individual risk of cancer? Guidelines advise heightened surveillance in certain women, including those with a family history of breast cancer and those with a BRCA mutation, but for average-risk women screening largely remains an age-based, one-size-fits-all proposition. More […]

Multiagent Adjuvant Therapy Ups Pancreatic Cancer Survival

Source link : https://www.newshealth.biz/health-news/multiagent-adjuvant-therapy-ups-pancreatic-cancer-survival/ TOPLINE: Adjuvant combination leucovorin calcium, fluorouracil, irinotecan hydrochloride, and oxaliplatin (FOLFIRINOX) and other multiagent chemotherapy regimens boost overall survival (OS) in patients with resected pancreatic adenocarcinoma after preoperative FOLFIRINOX. Single-agent adjuvant chemotherapy shows no significant survival benefit. METHODOLOGY: Researchers conducted a retrospective cohort study across 48 centers in 20 countries from […]

Huntington’s Disease: Can Beta Blockers Help?

Source link : https://www.newshealth.biz/health-news/huntingtons-disease-can-beta-blockers-help/ In a recent study, beta blockers appeared to significantly lower both the annualized risk for conversion from presymptomatic to symptomatic Huntington’s disease (HD) and the rate of worsening among symptomatic patients. Accordingly, authors suggested, beta blockers one day may play a role in treating HD, perhaps by blocking norepinephrine signaling or […]

IFSH Guides Surgical Decisions in OPSCC but Has Limitations

Source link : https://www.newshealth.biz/health-news/ifsh-guides-surgical-decisions-in-opscc-but-has-limitations/ Intraoperative frozen section histology (IFSH) demonstrates high diagnostic accuracy for individual surgical margins in human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC), but it may fall short in predicting final surgical margin status, according to the authors of new research. Despite the limitations of IFSH, it remains a key tool for […]