Nasal Spray Diuretic Evades Heart Failure Drug Flaw
Source link : https://www.newshealth.biz/health-news/nasal-spray-diuretic-evades-heart-failure-drug-flaw/ CHICAGO — A nasal spray formulation of bumetanide, a diuretic drug, could help treat heart failure by preventing the resistance that can develop to oral forms of the drug, a preliminary safety and efficacy study in healthy volunteers showed. Diuretic resistance is a common problem in patients with heart failure, said Eric […]
The Push for Off-Label Rx to Treat Long COVID: What Works?
Source link : https://www.newshealth.biz/health-news/the-push-for-off-label-rx-to-treat-long-covid-what-works/ Charlie McCone, a San Francisco marketing specialist, developed long COVID in 2020, recovered and developed it again in 2021. He’s been sick with fatigue and shortness of breath since then, spending many hours of every day in bed. Only one drug helped his shortness of breath, he said. But doctor after […]
Investigational Drugs Look Promising for Osteoarthritis Pain
Source link : https://www.newshealth.biz/health-news/investigational-drugs-look-promising-for-osteoarthritis-pain/ WASHINGTON — Investigational treatments aimed specifically at reducing pain in knee osteoarthritis (OA) are moving forward in parallel with disease-modifying approaches. “We still have very few treatments for the pain of osteoarthritis…It worries me that people think the only way forward is structure modification. I think while we’re waiting for some […]
Lucy Letby interviewed in prison over Liverpool baby deaths
Source link : https://www.newshealth.biz/health-news/lucy-letby-interviewed-in-prison-over-liverpool-baby-deaths/ Cheshire Constabulary Lucy Letby is serving 15 whole-life terms Lucy Letby has been interviewed by police in prison under caution as part of ongoing investigations into more baby deaths at two hospitals, Cheshire Constabulary has confirmed. The force said it had “recently” spoken to the former neonatal nurse over deaths and […]
Is Eastern Europe Missing Out?
Source link : https://www.newshealth.biz/health-news/is-eastern-europe-missing-out/ A new, long-acting injectable to prevent HIV infection could be a “game-changer” in ending the AIDS epidemic, if all who would benefit can access it. In the phase 3, double-blind, randomized, controlled trial PURPOSE 1, 100% of 2134 women aged 16-25 years in South Africa and Uganda who received a twice […]
Flu Shot Reminders Improve Use in Heart Attack Survivors
Source link : https://www.newshealth.biz/health-news/flu-shot-reminders-improve-use-in-heart-attack-survivors/ An electronic nudge explaining the cardiovascular benefits of the influenza vaccine increased vaccination rates, particularly among people who had previously had a heart attack, showed the NUDGE FLU series of clinical trials. Influenza has the potential to be a dangerous infection on its own, but it increases the risk for cardiovascular […]
Hospice leaders warn hundreds of beds out of use
Source link : https://www.newshealth.biz/health-news/hospice-leaders-warn-hundreds-of-beds-out-of-use/ Getty Images About 300 hospice inpatient beds are currently closed or out of use in England, hospice leaders have warned. They say a lack of funding and staff are the primary reasons why some of England’s 170 hospices have had to close beds permanently or take them out of use. Hospice […]
‘We’re attacked and abused as we try to save lives’
Source link : https://www.newshealth.biz/health-news/were-attacked-and-abused-as-we-try-to-save-lives/ BBC Nutan Patel-West said racist abuse and violent attacks had made her fearful while on duty Violence and abuse against paramedics and emergency call handlers is on the rise, with reported cases up by more than a third since 2019, the BBC has found. Almost 45,000 assaults were recorded by ambulance […]
Daily Chores May Provide Cardiovascular Protection in Women Who Don’t Exercise
Source link : https://www.newshealth.biz/health-news/daily-chores-may-provide-cardiovascular-protection-in-women-who-dont-exercise/ Short bursts of incidental daily activity were tied to fewer long-term major adverse cardiovascular events in women without a formal exercise routine. So-called “vigorous intermittent lifestyle physical activity” can be related to activities for one’s occupation, housework, or transportation. These findings were not observed in men, and sex-specific physical activity guidelines […]
Most Top Medical Journals Prohibit Use of AI During Peer Review Process
Source link : https://www.newshealth.biz/health-news/most-top-medical-journals-prohibit-use-of-ai-during-peer-review-process/ Most of the top 100 medical journals provide guidance on the use of artificial intelligence (AI) during the peer review process, with many explicitly prohibiting its use, a study showed. Of the 78 top journals that provide this guidance, 59% prohibit its use in peer review, while the rest allow its […]
Stem Cell Selection Unneeded for SSc Transplant Therapy?
Source link : https://www.newshealth.biz/health-news/stem-cell-selection-unneeded-for-ssc-transplant-therapy/ Autologous stem cell transplant for patients with diffuse systemic sclerosis (SSc), without selecting for a particular hematopoietic cell type, performed about as well in a new single-arm trial as was seen earlier with CD34+ stem cell transplant. Three-quarters of the study’s 20 patients survived 5 years without relapse or recurrence, and […]
Cognitive Performance Falls as Metal Exposure Rises
Source link : https://www.newshealth.biz/health-news/cognitive-performance-falls-as-metal-exposure-rises/ Metal exposure measured in urine was tied to lower cognitive performance and increased dementia risk. Having at least one copy of the APOE4 allele may modify this association. The study assessed exposure to both essential and non-essential metals. Traces of nine essential metals and non-essential metals in urine were linked with […]
Hello Buprenorphine, Step Into My Practice
Source link : https://www.newshealth.biz/health-news/hello-buprenorphine-step-into-my-practice/ Wakeman is an addiction medicine specialist and an associate professor of medicine. After years of alarming increases in opioid overdose deaths, the U.S. finally saw a 1-year decline from 84,000 to 81,000 in 2023. While the marginal drop is encouraging, we cannot rest on this achievement or count on it to […]
HIPEC for Recurrent, Platinum-Sensitive Ovarian Cancer Fails to Improve PFS
Source link : https://www.newshealth.biz/health-news/hipec-for-recurrent-platinum-sensitive-ovarian-cancer-fails-to-improve-pfs/ Patients with recurrent platinum-sensitive ovarian cancer did just as well with cytoreductive surgery alone as they did with surgery plus intraperitoneal chemotherapy, according to a randomized trial. Median progression-free survival (PFS) improved from 23 months with surgery alone to 25 months with the addition of hyperthermic intraperitoneal chemotherapy (HIPEC), a nonsignificant […]
Modified Donanemab Dosing May Reduce ARIA-E Risk in Early Alzheimer’s
Source link : https://www.newshealth.biz/health-news/modified-donanemab-dosing-may-reduce-aria-e-risk-in-early-alzheimers/ Modified titration of donanemab (Kisunla) for early Alzheimer’s disease significantly reduced the frequency of amyloid-related imaging abnormalities with edema and effusion (ARIA-E) compared to standard dosing, while maintaining sufficient amyloid reduction, according to findings from the TRAILBLAZER-ALZ 6 trial presented at the Clinical Trials on Alzheimer’s Disease conference in Madrid. In […]
Early Dementia Predictors; Neural Data Privacy; An Artist’s Journey Into Parkinson’s
Source link : https://www.newshealth.biz/health-news/early-dementia-predictors-neural-data-privacy-an-artists-journey-into-parkinsons/ A new RAND analysis evaluated the predictive power of 181 potential risk factors for cognitive impairment and dementia. Family mental illness history was associated with aggression risk in people with chronic traumatic encephalopathy, an autopsy study showed. (Neurology) Hypothalamic deep brain stimulation helped patients walk after spinal cord injury. (Nature Medicine) […]
Timelier U.S. Guidelines; Spouse’s Personality & CVD; ‘Hostile’ Cardiologists Out
Source link : https://www.newshealth.biz/health-news/timelier-u-s-guidelines-spouses-personality-hostile-cardiologists-out/ To facilitate more timely guideline updates, the American College of Cardiology and the American Heart Association have committed to annual guideline “maintenance” and single recommendation updating. (Journal of the American College of Cardiology) Having a spouse with a Type D (“distressed”) personality was associated with adverse cardiovascular outcomes for patients with […]
ADA Advises Against Compounded GLP-1s; Growth Hormone Therapy Guide; T1D Outcomes Up
Source link : https://www.newshealth.biz/health-news/ada-advises-against-compounded-glp-1s-growth-hormone-therapy-guide-t1d-outcomes-up/ The American Diabetes Association (ADA) urged healthcare providers against prescribing non-FDA approved compounded GLP-1 and dual GIP/GIP-1 receptor agonists for type 2 diabetes or obesity and instead recommended switching to a different FDA-approved medication if an agent is unavailable. (Diabetes Care) Patients with hypothyroidism who lost more than over 5 lb […]
Stone Workers Often Present With Atypical, Advanced Features of Silicosis
Source link : https://www.newshealth.biz/health-news/stone-workers-often-present-with-atypical-advanced-features-of-silicosis/ Workers who build engineered stone countertops often present with atypical and advanced features of silicosis, which may be missed by physicians, delaying diagnosis and treatment, according to findings from a cross-sectional pilot study. Among 21 workers who underwent preliminary analysis at a large urban safety-net hospital, 48% had atypical imaging features […]
Better Drugs Through AI? What Machine Learning Can Teach Big Pharma.
Source link : https://www.newshealth.biz/health-news/better-drugs-through-ai-what-machine-learning-can-teach-big-pharma/ Artificial intelligence (AI) is changing the way companies do business — helping programmers write code and fielding customer service calls with chatbots. But the pharmaceutical industry is still waiting to see whether AI can tackle its biggest challenge: finding faster, cheaper ways to develop new drugs. Despite billions poured into research, […]
Supreme Court Doesn’t Seem Convinced FDA Was Unfair in Blocking Flavored Vapes
Source link : https://www.newshealth.biz/health-news/supreme-court-doesnt-seem-convinced-fda-was-unfair-in-blocking-flavored-vapes/ A majority of Supreme Court justices didn’t seem convinced Monday that federal regulators misled companies before refusing to allow them to sell sweet-flavored vaping products following a surge in teen e-cigarette use. The conservative-majority court did raise questions about the FDA crackdown that included denials of more than a million nicotine […]
How monitoring your sweat could reveal the state of your health
Source link : https://www.newshealth.biz/health-news/how-monitoring-your-sweat-could-reveal-the-state-of-your-health/ Your sweat holds a lot of information about the state of your health Ryan Pierse/Getty Images Wow, you’re quite salty,” says Stefan van der Fluit, looking over my numbers. I could have told him that. I have just done a sweaty, 45-minute workout on an exercise bike and the salt is […]
Some Older Adults Think Stopping CRC Screening at Age 75 Is ‘Unacceptable’
Source link : https://www.newshealth.biz/health-news/some-older-adults-think-stopping-crc-screening-at-age-75-is-unacceptable/ Although a majority of older adults said that guidelines limiting colorectal cancer (CRC) screening after age 75 were acceptable, a substantial minority did not agree, according to results from a cross-sectional study. Among over 1,200 older adults, a weighted estimate of 60.4% said guidelines on stopping CRC screening at age 75 […]
Harvey Weinstein Hospitalized; Medicare Advantage Under Trump; NFL Icon’s Health
Source link : https://www.newshealth.biz/health-news/harvey-weinstein-hospitalized-medicare-advantage-under-trump-nfl-icons-health/ Note that some links may require registration or subscription. Former film producer Harvey Weinstein was hospitalized after an “alarming blood test.” (AP News) President-elect Donald Trump’s health nominees were COVID-19 skeptics. Politico analyzed how their COVID views have aged and what the evidence actually says. Medicare Advantage insurers are likely to […]
Why do Ozempic and Wegovy seem to treat everything?
Source link : https://www.newshealth.biz/health-news/why-do-ozempic-and-wegovy-seem-to-treat-everything/ It is rare that a drug becomes a household name and even rarer for one to become a superstar, but with its ability to grab headlines, Ozempic is the Taylor Swift of pharmaceuticals. So just what lies behind its star power? Even as the drug and its derivatives take off, researchers […]
BCG Vaccine May Protect Against Long COVID Symptoms
Source link : https://www.newshealth.biz/health-news/bcg-vaccine-may-protect-against-long-covid-symptoms/ TOPLINE: Administering the Bacillus Calmette-Guérin (BCG) vaccine during the active phase of COVID-19 may help protect against the development of long COVID. METHODOLOGY: A phase 3 clinical trial initiated in early 2020 investigated the effect of the BCG vaccine injected during active infection on COVID-19 progression in adults with mild or […]
Heart Benefits of Exercise Vary by Race, Exercise, Sex
Source link : https://www.newshealth.biz/health-news/heart-benefits-of-exercise-vary-by-race-exercise-sex/ Disparities in participation may be preventing women and racial and ethnic minorities from deriving the full cardiovascular benefits of exercise, according to a new review. Women derive greater cardiovascular benefits from exercise and have reduced rates of sudden cardiac death than men, according to the review. Moreover, Black race or ethnicity […]
Prasugrel Bests Ticagrelor in Acute Coronary Syndrome Care
Source link : https://www.newshealth.biz/health-news/prasugrel-bests-ticagrelor-in-acute-coronary-syndrome-care/ TOPLINE: Prasugrel is associated with lower rates of mortality, myocardial infarction (MI), and stroke than ticagrelor under conditions of routine care of patients discharged after invasive treatment for acute coronary syndrome, with the effects being particularly pronounced in those with ST-segment elevation MI (STEMI). METHODOLOGY: Researchers used data from a German […]
Is Bariatric Surgery at Risk of Becoming Obsolete?
Source link : https://www.newshealth.biz/health-news/is-bariatric-surgery-at-risk-of-becoming-obsolete/ The availability of second-generation obesity drugs (glucagon-like peptide 1 [GLP-1] analogues) has raised questions about the role of bariatric surgery. During its 40th annual congress in October 2024, the French Society of Endocrinology held a debate on this topic. Emmanuel Disse, MD, PhD, an endocrinologist at Lyon University Hospital, Lyon, argued […]
PFAS Exposure Can Impair Thyroid Homeostasis in Adults
Source link : https://www.newshealth.biz/health-news/pfas-exposure-can-impair-thyroid-homeostasis-in-adults/ TOPLINE: Exposure to individual or mixed per- and polyfluoroalkyl substances (PFASs) is associated with changes in peripheral rather than central thyroid hormone sensitivity. METHODOLOGY: PFASs are widely recognized for their persistence in the environment and potential endocrine-disrupting effects. A cross-sectional study investigated associations between PFAS exposures and thyroid homeostasis parameters in […]
Expert Discusses the ‘Four Pillars of Acne Pathogenesis’
Source link : https://www.newshealth.biz/health-news/expert-discusses-the-four-pillars-of-acne-pathogenesis/ LAS VEGAS — For clinicians who rely on generic tretinoin 0.5% as their go-to treatment for patients with acne, Shanna Miranti, MPAS, PA-C, offers some straightforward advice: You can do better. Shanna Miranti, MPAS, PA-C “Friends don’t let friends write generic tretinoin only because there are so many better options out […]
Covid corruption commissioner gets to work
Source link : https://www.newshealth.biz/health-news/covid-corruption-commissioner-gets-to-work/ The new Covid corruption commissioner has started an investigation into personal protective equipment (PPE) fraud. Tom Hayhoe’s first task will be reviewing the £8.7bn of PPE bought during the pandemic that then had to be written off the government’s books. Mr Hayhoe is also likely to review the previous government’s abandoning […]
All Docs Need More Tech Training
Source link : https://www.newshealth.biz/health-news/all-docs-need-more-tech-training/ Artificial intelligence (AI) is already changing healthcare, but data science training for clinicians and medical students is still largely elective. The vast majority of doctors believe that needs to change. According to a soon-to-be-published Medscape report, AI Adoption in Healthcare, 85% of practicing physicians agreed: The use of AI in medicine […]
ADA Advises Against Using Compounded GLP-1 RA Medications
Source link : https://www.newshealth.biz/health-news/ada-advises-against-using-compounded-glp-1-ra-medications/ In a new statement, the American Diabetes Association (ADA) has advised against the use of compounded glucagon-like peptide 1 receptor agonist (GLP-1 RA) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RA medication classes. The ADA recommends GLP-1 RA and GIP/GLP-1 RA medications approved by the US Food and Drug Administration (FDA) for […]
FDA Approves Ustekinumab Biosimilar Yesintek
Source link : https://www.newshealth.biz/health-news/fda-approves-ustekinumab-biosimilar-yesintek/ The US Food and Drug Administration (FDA) has approved ustekinumab-kfce (Yesintek) as a biosimilar to ustekinumab (Stelara) for the treatment of Crohn’s disease, ulcerative colitis, plaque psoriasis, and psoriatic arthritis. This is the sixth ustekinumab biosimilar approved by the FDA. The biosimilar was developed by Biocon Biologics, a biosimilars company based […]
Consider All Prior Fractures During Osteoporosis Assessment, Study Suggests
Source link : https://www.newshealth.biz/health-news/consider-all-prior-fractures-during-osteoporosis-assessment-study-suggests/ Fractures that occurred at any prior time in adulthood were associated with fracture risk in older adults, a cohort study indicated. In fact, a first fracture in younger adulthood was linked with the greatest increased risk. Compared with no fracture, any non-high-trauma fracture during ages 20 to 39 years was associated […]
Study: Patients Better Be Very Literate to Understand These Handouts
Source link : https://www.newshealth.biz/health-news/study-patients-better-be-very-literate-to-understand-these-handouts/ Patient education materials (PEMs) in rheumatology and general medicine demanded greater literacy than is typically recommended, researchers found. Handouts from the American College of Rheumatology (ACR) and the JAMA Network group required a 10th-grade reading level on average by one metric, and a college-sophomore level by another, according to Yazmin Rustomji, […]
Drug Prices Negotiated by Medicare Still Higher Than Other Countries’
Source link : https://www.newshealth.biz/health-news/drug-prices-negotiated-by-medicare-still-higher-than-other-countries/ Prices for the first 10 drugs negotiated by Medicare fell from their initial net prices, but all drugs except one remained more expensive in the U.S. than in peer countries, researchers said. Compared with their net prices prior to negotiation, negotiated prices for the 10 drugs ranged from 8% lower for […]
Beta-Blockers Tied to Delayed Huntington’s Disease Progression
Source link : https://www.newshealth.biz/health-news/beta-blockers-tied-to-delayed-huntingtons-disease-progression/ Beta-blocker use was tied with slower symptom progression in people with early motor-manifest Huntington’s disease. In a people with genetically confirmed premanifest Huntington’s, beta-blocker use was associates with a later age at symptom onset. The autonomic nervous system may be a novel target to help slow Huntington’s progression. Beta-blocker therapy was […]
Long List of Tasks Awaits New CDC Director, Experts Say
Source link : https://www.newshealth.biz/health-news/long-list-of-tasks-awaits-new-cdc-director-experts-say/ Former representative Dave Weldon, MD (R-Fla.), President-elect Donald Trump’s pick to run the CDC, will have his work cut out for him, one infectious disease expert says. Anne Schuchat, MD, former principal deputy director of the CDC, said that among the critical duties for Weldon, should he be confirmed by the […]
Indoor Air Purification Improved Pulmonary Health in Kids
Source link : https://www.newshealth.biz/health-news/indoor-air-purification-improved-pulmonary-health-in-kids/ Indoor air purification improved pulmonary health markers among children living in a region with severe air pollution, a cluster randomized trial showed. Among 79 kids living in Mengzhou City in China, the time-weighted personal fine particulate matter concentration decreased by 45.14% during the air purification period (mean 21.49 μg/m3) compared with […]
Fat in the Belly Correlates With Brain Amyloid
Source link : https://www.newshealth.biz/health-news/fat-in-the-belly-correlates-with-brain-amyloid/ Higher levels of visceral fat were correlated with more amyloid plaque in the brains of cognitively normal individuals, according to a study that hints as to why individuals with obesity are more prone to dementia. Amyloid levels were higher among individuals with obesity compared to those without obesity (P=0.008), and were […]
Myelofibrosis: Transformation to Leukemia | MedPage Today
Source link : https://www.newshealth.biz/health-news/myelofibrosis-transformation-to-leukemia-medpage-today/ A subset of patients with myeloproliferative neoplasms (MPNs) — clonal disorders of hematopoietic stem cells that include polycythemia vera and essential thrombocythemia, as well as primary myelofibrosis — will transition to post-MPN, or secondary, acute myeloid leukemia (AML). “Some people call it AML — I like to make the distinction and […]
Novel Therapies for Asthma in the Pipeline
Source link : https://www.newshealth.biz/health-news/novel-therapies-for-asthma-in-the-pipeline/ In this exclusive MedPage Today video, Michael E. Wechsler, MD, a pulmonologist at National Jewish Health in Denver, discusses some of the novel treatments and strategies that he believes are going to have the potential to benefit patients with severe asthma over the next few years. Following is a transcript of […]
What If…? | MedPage Today
Source link : https://www.newshealth.biz/health-news/what-if-medpage-today/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. Over this past long Thanksgiving holiday weekend, in addition to eating way too much turkey and stuffing, and being thankful […]
Fauci Facepalms Won’t Cut It in the Second Trump Administration
Source link : https://www.newshealth.biz/health-news/fauci-facepalms-wont-cut-it-in-the-second-trump-administration/ Oxman is an intensive care physician and associate professor of medicine. It was one of the more memorable images of the COVID pandemic. Anthony Fauci, MD, a prominent member of the White House COVID task force and director of the National Institute of Allergy and Infectious Diseases, stands at the back […]
HIV Doesn’t Cause AIDS and Other Conspiracies RFK Jr. Endorsed
Source link : https://www.newshealth.biz/health-news/hiv-doesnt-cause-aids-and-other-conspiracies-rfk-jr-endorsed/ Robert F. Kennedy Jr.’s views on vaccines are well known, but the environmental lawyer tapped by President-elect Donald Trump to be the next HHS Secretary has touted other questionable claims, from man-made chemicals turning children gay to antidepressants being responsible for mass shootings. Here are a few. That HIV Does Not […]
A Twice-Yearly Shot Could Help End AIDS. But Will It Get to Everyone Who Needs It?
Source link : https://www.newshealth.biz/health-news/a-twice-yearly-shot-could-help-end-aids-but-will-it-get-to-everyone-who-needs-it/ It’s been called the closest the world has ever come to a vaccine against HIV. The twice-yearly shot was 100% effective in preventing HIV infections in a study of women, and results published Wednesday show it worked nearly as well in men. Drugmaker Gilead said it will allow cheap, generic versions […]
The Supreme Court Takes Up Tennessee’s Ban on Gender-Affirming Care for Minors
Source link : https://www.newshealth.biz/health-news/the-supreme-court-takes-up-tennessees-ban-on-gender-affirming-care-for-minors/ Advocates for transgender rights are turning to a conservative-dominated Supreme Court after a presidential election in which Donald Trump and his allies promised to roll back protections for transgender people. The justices on Wednesday are taking up the issue of gender-affirming care for transgender minors, which has been banned by Tennessee […]
When, and where, did the covid-19 pandemic really begin?
Source link : https://www.newshealth.biz/health-news/when-and-where-did-the-covid-19-pandemic-really-begin/ People carrying out disinfection work at a market in Wuhan, where covid-19 is thought to have originated, in March 2020 An Yuan/China News Service via Getty Images Five years ago, the covid-19 pandemic was getting under way – but we didn’t know it yet. So, what exactly happened? Many scientists are […]
Year in Review: Multiple Myeloma
Source link : https://www.newshealth.biz/health-news/year-in-review-multiple-myeloma/ Advances in multiple myeloma treatment this year were marked by the resurrection of a drug that had been previously pulled off the market, new FDA approvals, and research suggesting that an isatuximab (Sarclisa)-based quadruplet could be the new standard of care for transplant-ineligible patients with newly diagnosed disease. A Second Chance […]
Doc Murdered 8 Patients? RFK Jr. Will ‘Cost Lives’; $412M in Penile Injection Case
Source link : https://www.newshealth.biz/health-news/doc-murdered-8-patients-rfk-jr-will-cost-lives-412m-in-penile-injection-case/ Note that some links may require registration or subscription. A palliative care physician in Germany is suspected of murdering eight elderly patients receiving at-home care, and then setting some of their homes on fire to cover up the crimes. (CBS News) The Supreme Court on Monday will hear oral arguments over […]
US Supreme Court to Scrutinize FDA Denial Of Flavored Vape Products
Source link : https://www.newshealth.biz/health-news/us-supreme-court-to-scrutinize-fda-denial-of-flavored-vape-products/ WASHINGTON (Reuters) – The U.S. Supreme Court is set on Monday to hear the U.S. Food and Drug Administration’s defense of the agency’s refusal to let two e-cigarette companies sell flavored vape products that regulators found to pose a significant health risk to youths. The FDA under outgoing Democratic President Joe […]
Novocure’s Pancreatic Cancer Treatment Meets Main Goal in Late-stage Study
Source link : https://www.newshealth.biz/health-news/novocures-pancreatic-cancer-treatment-meets-main-goal-in-late-stage-study/ (Reuters) – Novocure said on Monday its experimental therapy extended the lives of patients with a form of advanced pancreatic cancer when combined with chemotherapy, achieving the primary goal in a late-stage trial. The therapy uses Tumor Treating Fields, or electric fields, to kill cancer cells while sparing most nearby healthy […]
Catheter AF Ablation Growing in Popularity and Complexity
Source link : https://www.newshealth.biz/health-news/catheter-af-ablation-growing-in-popularity-and-complexity/ Catheter ablation is fast becoming one of the safest and most effective treatments for atrial fibrillation (AF) as new technologies become increasingly available to treat a wide spectrum of the roughly 40 million people worldwide with the condition. In a recently published policy statement, the Heart Rhythm Society pointed out that […]
Accelerated Approval of New TKI Use in CML Sparks Questions
Source link : https://www.newshealth.biz/health-news/accelerated-approval-of-new-tki-use-in-cml-sparks-questions/ US regulators’ use of a speedy clearance pathway for a new frontline indication for asciminib for chronic myeloid leukemia (CML) has raised questions due to the number of medications already available for this condition. In October, the US Food and Drug Administration (FDA) granted accelerated approval to asciminib (Scemblix, Novartis AG) […]
Is 1-Week Radiotherapy Safe for Breast Cancer?
Source link : https://www.newshealth.biz/health-news/is-1-week-radiotherapy-safe-for-breast-cancer/ TOPLINE: At 1 year, 82% of patients with breast cancer who received a 1-week ultrahypofractionated breast radiotherapy regimen reported no or mild toxicities. Most patients also reported that the reduced treatment time was a major benefit of the 1-week radiotherapy schedule. METHODOLOGY: In March 2020, during the COVID-19 pandemic, international and […]
Cardiometabolic Impact on Liver and Pancreatic Fat Depots
Source link : https://www.newshealth.biz/health-news/cardiometabolic-impact-on-liver-and-pancreatic-fat-depots/ TOPLINE: A link between hepatic fat and intrapancreatic fat deposition (IPFD) in young and middle-aged adults without obesity and with low lipids and blood sugar seems to disappear in older adults with obesity and high lipids or blood sugar, suggesting interventions to reduce both fat depots may be more effective in […]
New Leukemia Txs, Fewer Blood Clots With GLP-1 Rxs
Source link : https://www.newshealth.biz/health-news/new-leukemia-txs-fewer-blood-clots-with-glp-1-rxs/ SAN DIEGO — Groundbreaking studies into leukemia treatments and the effects of glucagon-like peptide 1 (GLP-1) inhibitors on venous thromboembolism (VTE) risk will be presented on December 9-12 at the American Society of Hematology (ASH) 2024 Annual Meeting, according to association leaders who spoke in a media preview session. Here’s a […]
Sotagliflozin Helps Manage Anemia in T2D and CKD
Source link : https://www.newshealth.biz/health-news/sotagliflozin-helps-manage-anemia-in-t2d-and-ckd/ TOPLINE: Sotagliflozin, a dual sodium-glucose cotransporter 1 and 2 inhibitor, rapidly improves hemoglobin levels in patients with type 2 diabetes (T2D) and moderate to severe chronic kidney disease (CKD), regardless of whether anemia is present at baseline. METHODOLOGY: Although erythropoiesis-stimulating agents can boost hemoglobin levels, they also elevate the risk for […]
Belly Fat Beats BMI in Predicting Colorectal Cancer Risk
Source link : https://www.newshealth.biz/health-news/belly-fat-beats-bmi-in-predicting-colorectal-cancer-risk/ TOPLINE: Individuals with normal body mass index (BMI) measurements may still face an increased risk for colorectal cancer (CRC) if they have central obesity, characterized by excess fat around the abdomen. METHODOLOGY: General obesity, often measured using BMI, is a recognized risk factor for CRC, but how much of this association […]
Vorasidenib for Certain IDH-Mutant Gliomas: Is It Worth It?
Source link : https://www.newshealth.biz/health-news/vorasidenib-for-certain-idh-mutant-gliomas-is-it-worth-it/ The emergence of vorasidenib, the first targeted therapy for certain gliomas with IDH mutations, has ignited a wave of excitement in both patient and physician spaces. After years with limited treatment options, experts hailed vorasidenib “a promising breakthrough,” “a paradigm shift,” a “new hope,” and “probably the most important advance in […]
Vulnerability to Emotional Contagion May Stress Older Adults
Source link : https://www.newshealth.biz/health-news/vulnerability-to-emotional-contagion-may-stress-older-adults/ Older adults who are sensitive to the distress of others are more likely to feel anxious or depressed themselves because of a psychological mechanism called “emotional contagion,” researchers suggested. Emotional contagion is an adaptive response that occurs unconsciously when people mimic the facial expressions, gestures, and postures of others, leading to […]
AMR Could Surpass Cancer as Leading Cause of Death by 2050
Source link : https://www.newshealth.biz/health-news/amr-could-surpass-cancer-as-leading-cause-of-death-by-2050/ Antimicrobial resistance (AMR) is globally recognized as one of the greatest health threats of the 21st century, responsible for 1.27 million deaths annually. “According to the WHO, if no measures are taken promptly, AMR could lead to more deaths than cancer by 2050,” said Arnaud Marchant, MD, PhD, director of the […]
Cognitive Decline in AF Not Reduced by Anticoagulation
Source link : https://www.newshealth.biz/health-news/cognitive-decline-in-af-not-reduced-by-anticoagulation/ CHICAGO — A randomized placebo-controlled trial testing a direct oral anticoagulant for the prevention of cognitive decline in patients with atrial fibrillation (AF) has been halted early for futility. After a median follow-up of 3.7 years, there was no difference between rivaroxaban 15 mg and placebo for a composite primary endpoint […]
Wearable tech can monitor our health but why are doctors so sceptical?
Source link : https://www.newshealth.biz/health-news/wearable-tech-can-monitor-our-health-but-why-are-doctors-so-sceptical/ Oura Smart rings have built-in sensors that monitor the wearer’s heart rate and other health issues Wearable tech – currently dominated by smart watches – is a multi-billion dollar industry with a sharp focus on health tracking. Many premium products claim to accurately track exercise routines, body temperature, heart rate, menstrual […]
People on Breathing Machines Struggle Without Power After Weather Disasters
Source link : https://www.newshealth.biz/health-news/people-on-breathing-machines-struggle-without-power-after-weather-disasters/ HOUSTON — Kimberly Rubit had one priority in mind as Hurricane Beryl ripped through Houston this summer: her severely disabled daughter. The 63-year-old worked nonstop to prevent Mary, 42, from overheating without air conditioning, water, or lights after Beryl knocked out power to their home for 10 days. At least three […]
Medical Education Needs Its Own AI Playbook
Source link : https://www.newshealth.biz/health-news/medical-education-needs-its-own-ai-playbook/ Kanaparthy is a practicing internal medicine physician specializing in clinical informatics. President-elect Donald Trump’s pick for secretary of education, Linda McMahon, will be wrestling with growing uncertainty around education in the age of artificial intelligence (AI) in the years ahead if she’s confirmed by the Senate. In medical education in particular, […]
Should RSV Vaccination Expand to Younger High-Risk Groups?
Source link : https://www.newshealth.biz/health-news/should-rsv-vaccination-expand-to-younger-high-risk-groups/ Although the FDA has expanded approvals for two respiratory syncytial virus (RSV) vaccines to include high-risk young and middle-age adults, CDC advisors have not yet moved to recommend the vaccine in these groups. In June, the FDA expanded the approval of GSK’s RSV vaccine (Arexvy) for use in adults ages 50 […]
Terminally ill people react after MPs vote
Source link : https://www.newshealth.biz/health-news/terminally-ill-people-react-after-mps-vote/ BBC Nik Ward is disappointed the bill has passed and worries about its implications for vulnerable people Terminally ill people are a step closer to being able to choose when they die after MPs voted to support a proposed change to the law. The right to an assisted death will be […]
Anger after infected blood compensation put on hold
Source link : https://www.newshealth.biz/health-news/anger-after-infected-blood-compensation-put-on-hold/ PA Media A public inquiry described the scale of the scandal as “horrifying” Some victims of the infected blood scandal have been told interim compensation payments of £100,000 due to be made before Christmas have been put on hold. It is thought at least 10 bereaved families have received letters saying […]
Benefits of HPV Vaccination; Contraindications to Newer Obesity Drugs
Source link : https://www.newshealth.biz/health-news/benefits-of-hpv-vaccination-contraindications-to-newer-obesity-drugs/ TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center in El Paso, look at the top medical stories of the week. This week’s topics include […]
Worried About Healthcare Worker Well-Being?
Source link : https://www.newshealth.biz/health-news/worried-about-healthcare-worker-well-being/ Simmons is Chief Medical Officer of the Dr. Lorna Breen Heroes’ Foundation. Lorna Breen, MD, Matt Gall, MD, Mo Brown, MD, Scott Jolley, MD, William West Jr., MD, and Tristin Smith, RN, are tragic examples of an unacceptably high level of suicide among U.S. healthcare workers. Unfortunately, this list could extend […]
Expanded Treatment Options for Primary Biliary Cholangitis Leave Open Questions
Source link : https://www.newshealth.biz/health-news/expanded-treatment-options-for-primary-biliary-cholangitis-leave-open-questions/ The approval of ursodeoxycholic acid (UDCA) for primary biliary cholangitis (PBC) in 1997 marked a pivotal turning point in management of the condition, substantially reducing the risk of liver transplant and death. However, UDCA’s arrival was not a panacea for all patients with PBC. Up to 40% of patients with PBC […]
How Ultra-processed Foods Drive Obesity, Metabolic Risks
Source link : https://www.newshealth.biz/health-news/how-ultra-processed-foods-drive-obesity-metabolic-risks/ Share on Pinterest David Petrus Ibars/Getty ImagesA new study finds that higher intake of ultra-processed foods is associated with greater body mass index (BMI). David Petrus Ibars/Getty Images A new study finds that higher ultra-processed food (UPF) intake is associated with an increased body mass index (BMI). The link between UPFs […]
Tears, hope and fear as assisted dying bill passed
Source link : https://www.newshealth.biz/health-news/tears-hope-and-fear-as-assisted-dying-bill-passed/ EPA On Friday, after weeks of fierce and passionate debate, MPs began their formal scrutiny of the bill that would allow terminally ill adults expected to die within six months to seek help to end their own life. It was a day of tears, hope, relief and fear. This is the […]
Fix palliative care before allowing assisted dying
Source link : https://www.newshealth.biz/health-news/fix-palliative-care-before-allowing-assisted-dying/ Getty Images Fixing the struggling palliative care system must be an immediate priority for the government, now that MPs have backed changing the law to allow assisted dying, senior doctors say. The Association for Palliative Medicine (APM) says there is a risk the funding needed to pay for doctors and the […]