Bowel cancer is rising in younger people around the world
Source link : https://www.newshealth.biz/health-news/bowel-cancer-is-rising-in-younger-people-around-the-world/ It isn’t entirely clear why bowel cancer is on the rise among adults under 50 STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY Rates of bowel cancer in younger adults have increased in countries around the world, though the trend appears to be most common in high-income nations. Previous studies have shown that bowel, or […]
Oral SERD Impresses in Advanced Breast Cancer With ESR1 Mutations
Source link : https://www.newshealth.biz/health-news/oral-serd-impresses-in-advanced-breast-cancer-with-esr1-mutations/ SAN ANTONIO — Among patients with estrogen receptor (ER)-positive, HER2-negative advanced breast cancer, treatment with imlunestrant did not significantly improve progression-free survival (PFS) compared with standard endocrine therapy, except in those with ESR1 mutations, the phase III EMBER-3 trial showed. Among 256 patients with these mutations, the median PFS was 5.5 […]
Could Psoriasis Treatment Be This Simple?
Source link : https://www.newshealth.biz/health-news/could-psoriasis-treatment-be-this-simple/ A derivative of the diuretic drug amiloride (Midamor) blocked key inflammatory pathways in mouse models of psoriasis, including xenografts of psoriatic human skin, as well as in cultured patient skin samples, researchers said. Skin cells taken from human psoriasis patients, reconstructed into tissue and grafted onto immunodeficient mice, “showed pronounced psoriasiform […]
One CAR T-Cell Therapy for Multiple Myeloma Tops Another in Propensity Matched Study
Source link : https://www.newshealth.biz/health-news/one-car-t-cell-therapy-for-multiple-myeloma-tops-another-in-propensity-matched-study/ SAN DIEGO — In a propensity-matched comparison of two CAR T-cell therapies, ciltacabtagene autoleucel (cilta-cel, Carvykti) demonstrated better efficacy than idecabtagene vicleucel (ide-cel, Abecma) for relapsed/refractory multiple myeloma, but had a higher rate of severe toxicity. A chart review of patients treated outside of clinical trials showed that 70% of patients […]
Britain Indefinitely Bans Puberty Blockers for Children With Gender Dysphoria
Source link : https://www.newshealth.biz/health-news/britain-indefinitely-bans-puberty-blockers-for-children-with-gender-dysphoria/ The British government on Wednesday indefinitely banned puberty blockers for children with gender dysphoria after independent experts found there was an unacceptable safety risk in prescribing the medication. The decision, which will be revisited in 2027, effectively bans a common approach to medical gender transitions for youths. It also goes against […]
Fighting Misinformation Like a Doctor
Source link : https://www.newshealth.biz/health-news/fighting-misinformation-like-a-doctor/ Thomas is a hospitalist in New York State. My first encounter with each patient follows a similar pattern. I hit the hand sanitizer near the door, stroll in rubbing it into my hands, and greet them. “Ms. K? Hi! I’m Dr. Joseph Thomas, I’m from Internal Medicine and I’ll be helping […]
Doc Accused of Patient Harm; Healthcare Hero’s Evolution; CHOP Downplayed Risks?
Source link : https://www.newshealth.biz/health-news/doc-accused-of-patient-harm-healthcare-heros-evolution-chop-downplayed-risks/ Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Oncologist Allegedly Harmed Patients While Earning Millions Thomas C. Weiner, MD, an oncologist at St. Peter’s Hospital in Helena, Montana, continued to practice medicine even while other physicians and administrators suspected he […]
Cancer Patients Who Completed Medication Survey Received More Help From Pharmacists
Source link : https://www.newshealth.biz/health-news/cancer-patients-who-completed-medication-survey-received-more-help-from-pharmacists/ NEW ORLEANS — Patients who completed a questionnaire monitoring the use of their new anticancer medications received more and faster interventions from pharmacists to address adverse events (AEs), a single-center randomized study showed. Though the number of AE-related interventions by pharmacists within 45 days was not significantly different for patients who […]
California Child May Have Bird Flu After Drinking Raw Milk
Source link : https://www.newshealth.biz/health-news/california-child-may-have-bird-flu-after-drinking-raw-milk/ A possible case of H5N1 bird flu virus in a California child has been linked to raw milk consumption and is under investigation by state health officials and the CDC. The patient experienced fever and vomiting after drinking raw milk and has since recovered, according to an announcement by Marin County […]
For Now, ‘Dreamers’ Will Be Shut Out of the Healthcare Marketplace in 19 States
Source link : https://www.newshealth.biz/health-news/for-now-dreamers-will-be-shut-out-of-the-healthcare-marketplace-in-19-states/ Young adult immigrants known as “Dreamers” in 19 U.S. states will be temporarily blocked from getting health insurance through the Affordable Care Act’s (ACA’s) public marketplace, a federal judge has ruled, limiting an effort by the Biden administration to help immigrants brought to the country illegally as children. Judge Daniel Traynor […]
Am I ‘Too Competitive’ for Some Residency Programs?
Source link : https://www.newshealth.biz/health-news/am-i-too-competitive-for-some-residency-programs/ Omer Awan is vice chair and associate program director for the diagnostic radiology residency at the University of Maryland School of Medicine in Baltimore. He has expertise in radiology, education, and public health. Follow Welcome to “Ask the Program Director,” a column from MedPage Today where your most pressing questions about […]
Indefinite ban on puberty blockers to be introduced
Source link : https://www.newshealth.biz/health-news/indefinite-ban-on-puberty-blockers-to-be-introduced/ The ban on giving puberty blockers to under-18s questioning their gender identify is to be made permanent, Health Secretary Wes Streeting says. Streeting told the House of Commons he was making the temporary ban currently in place indefinite across the UK, following a consultation and advice from the Commission on Human […]
Trial Data Helped Guide Treatment of Stage II-III Triple-Negative Breast Cancer
Source link : https://www.newshealth.biz/health-news/trial-data-helped-guide-treatment-of-stage-ii-iii-triple-negative-breast-cancer/ Even when diagnosed early, triple-negative breast cancer (TNBC) has a higher mortality rate compared with other breast cancer subtypes due to its aggressive nature. However, results from the randomized KEYNOTE-522 study showed an improvement in overall survival (OS) in patients with stage II-III TNBC who received pembrolizumab (Keytruda) before and after […]
Pirtobrutinib Delays Progression in CLL Already Treated With a BTK Inhibitor
Source link : https://www.newshealth.biz/health-news/pirtobrutinib-delays-progression-in-cll-already-treated-with-a-btk-inhibitor/ SAN DIEGO — Pirtobrutinib (Jaypirca) delayed disease progression versus other available options in patients with chronic lymphocytic leukemia (CLL) who had previously received a covalent Bruton’s tyrosine kinase (BTK) inhibitor, a phase III study showed. Median progression-free survival (PFS) reached 14 months with pirtobrutinib, an oral non-covalent BTK inhibitor, as compared […]
Pre-eclampsia could be treated with mRNA technology
Source link : https://www.newshealth.biz/health-news/pre-eclampsia-could-be-treated-with-mrna-technology/ High blood pressure is a common symptom of pre-eclampsia Nataliya Piatrovich/Alamy Delivering babies early, when possible, is currently the only way to deal with the common pregnancy complication pre-eclampsia. But the condition has now been successfully treated in mice by delivering mRNA molecules to the placenta to boost the growth of […]
Melanoma Mortality Rises at 0.8-mm Thickness, Study Finds
Source link : https://www.newshealth.biz/health-news/melanoma-mortality-rises-at-0-8-mm-thickness-study-finds/ TOPLINE: The risk for melanoma-related death was higher in individuals with tumors with a Breslow thickness of 0.8-1.0 mm than in individuals with tumors smaller than 0.8 mm, in an Australian study that used registry data. METHODOLOGY: The study analyzed 144,447 individuals (median age, 56 years, 54% men) diagnosed with thin […]
Jamie Foxx Reveals Diagnosis; Genital Herpes Prevalence; Dr. Oz’s Stand on Medicare
Source link : https://www.newshealth.biz/health-news/jamie-foxx-reveals-diagnosis-genital-herpes-prevalence-dr-ozs-stand-on-medicare/ Note that some links may require registration or subscription. Jamie Foxx revealed details about his 2023 near-death experience, saying he had a brain bleed and stroke that left him in a coma for 20 days. (CBS News) The H5N1 case in the California child whose infection was reported in November resembled […]
Tafasitamab-Based Combination Boosts PFS in Relapsed/Refractory Follicular Lymphoma
Source link : https://www.newshealth.biz/health-news/tafasitamab-based-combination-boosts-pfs-in-relapsed-refractory-follicular-lymphoma/ SAN DIEGO — Adding the humanized CD19-targeted monoclonal antibody tafasitamab (Monjuvi) to a backbone of lenalidomide (Revlimid) and rituximab (Rituxan) resulted in a significant and clinically meaningful improvement in progression-free survival (PFS) for patients with relapsed/refractory follicular lymphoma, the randomized phase III inMIND trial showed. Patients who received the combination had […]
At-Home Sleep Tests or Overnight Lab Trip for Kids?
Source link : https://www.newshealth.biz/health-news/at-home-sleep-tests-or-overnight-lab-trip-for-kids/ In many parts of the country, children and their parents face months-long wait times for sleep tests at labs. With obesity rising among the pediatric population, at-home sleep tests to assess sleep apnea and other disorders may be a more accessible and less expensive option. But regulators have only approved a […]
Eight women develop cancer ‘after smear misread’
Source link : https://www.newshealth.biz/health-news/eight-women-develop-cancer-after-smear-misread/ Science Photo Library A further 11 women’s slides were found to have pre-cancerous changes in the cells when reviewed Eight women whose smear tests were misread by screeners went on to develop cancer, a major review into cervical screening at the Southern Health Trust has found. A further 11 women’s slides […]
Eye Toxicities Are a Growing Concern With Certain ADCs
Source link : https://www.newshealth.biz/health-news/eye-toxicities-are-a-growing-concern-with-certain-adcs/ Despite being a targeted therapy, antibody-drug conjugates (ADCs) can cause significant off-target toxicity to the eyes of patients being treated for advanced multiple myeloma or cervical cancer, yet the risks remain relatively unknown, according to oncologists and ophthalmologists. Such experts called for greater collaboration between oncologists and ophthalmologists, in interviews with […]
Radiology Residencies: Hard to Find, Hard to Land
Source link : https://www.newshealth.biz/health-news/radiology-residencies-hard-to-find-hard-to-land/ Interest is up for radiology residencies, but available positions don’t match demand. Radiologists say the problem can be fixed. Medscape Medical News Source link : https://www.medscape.com/viewarticle/us-radiology-residencies-more-applicants-than-slots-2024a1000mvt?src=rss Author : Publish date : 2024-12-11 13:09:13 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date : 2024-12-11 13:09:13 […]
What Now for Factor XI Inhibitors in AF
Source link : https://www.newshealth.biz/health-news/what-now-for-factor-xi-inhibitors-in-af/ Factor XI inhibition was potentially the Goldilocks anticoagulant target with the promise of a reduction in thrombotic risk without a significant increase in bleeding. The early phase 2 data were encouraging, and the trials in orthopedic patients looked good. Then the phase 3 OCEANIC-AF, trial comparing the novel factor XI inhibitor asundexian […]
Med Schools Navigate Admissions in New Legal, Political Env
Source link : https://www.newshealth.biz/health-news/med-schools-navigate-admissions-in-new-legal-political-env/ A year and a half after the Supreme Court struck down the consideration of race or ethnicity in college admissions, the medical community awaits a moment of truth. The Association of American Medical Colleges (AAMC) is expected to soon release demographic data for the class of 2028 — the first to […]
Women Largely Unaware of ASM Risks, More Education Needed
Source link : https://www.newshealth.biz/health-news/women-largely-unaware-of-asm-risks-more-education-needed/ LOS ANGELES — The majority of women with epilepsy are inadequately educated about the potential risks associated with anti-seizure medications (ASMs), which include teratogenicity and a reduction in the efficacy of hormonal birth control, early results of a new survey suggested. In addition, only about a third of survey respondents indicated […]
A Q&A With Daniel C. Butler, MD
Source link : https://www.newshealth.biz/health-news/a-qa-with-daniel-c-butler-md/ Daniel C. Butler, MD, is associate professor of dermatology and director of the new Inflammatory and Aging Skin Research Program in the Division of Dermatology at the University of Arizona College of Medicine, Tucson, Arizona. Before returning to Arizona, where he had attended medical school, Butler practiced and was a researcher […]
Burn Resuscitation Volume Linked to Neurologic Risk
Source link : https://www.newshealth.biz/health-news/burn-resuscitation-volume-linked-to-neurologic-risk/ TOPLINE: Patients receiving > 200 mL/kg of fluid resuscitation for burn injuries show higher rates of worsening neurologic findings on imaging, with follow-up scans showing deterioration in high-volume recipients compared with low-volume recipients. METHODOLOGY: Researchers conducted a single-center retrospective review of 5176 patients with burn injuries who were admitted to a […]
USPSTF Updates Recommendations on Cervical Cancer Screening
Source link : https://www.newshealth.biz/health-news/uspstf-updates-recommendations-on-cervical-cancer-screening/ The US Preventive Services Task Force (USPSTF) has posted a draft updated statement on cervical cancer screening. The statement is open for public comment until January 13, 2025, on the task force’s website. Nearly all cases of cervical cancer are caused by human papilloma virus (HPV) and most occur in women […]
Dying in the Hospital: A Necessary Choice?
Source link : https://www.newshealth.biz/health-news/dying-in-the-hospital-a-necessary-choice/ More than a third of all patients with cancer die in hospitals, a figure that has increased slightly in recent years, while deaths at home have decreased. These findings come from a recent study published in Cancer Epidemiology, which analyzed data on the different places in Italy where end of life […]
Your Guide to COVID Vaccines for 2024-2025
Source link : https://www.newshealth.biz/health-news/your-guide-to-covid-vaccines-for-2024-2025/ Dec. 9, 2024 — The updated COVID vaccines for 2024-2025 are officially here, designed to target the latest variants and offer robust protection — but getting Americans to roll up their sleeves could prove harder than ever. With COVID cases on the decline, many people feel the urgency has passed. As […]
Bird flu suddenly got serious in 2024, infecting dozens of people
Source link : https://www.newshealth.biz/health-news/bird-flu-suddenly-got-serious-in-2024-infecting-dozens-of-people/ Cattle herds across the US caught bird flu this year Suzanne Kreiter/The Boston Globe via Getty Images A highly infectious type of bird flu began spreading in dairy cows across the US earlier this year, providing the pathogen with one of its best opportunities to date to evolve and more easily […]
CGM Use, GLP-1s, Drinking Water Key of 2025 ADA Standards
Source link : https://www.newshealth.biz/health-news/cgm-use-glp-1s-drinking-water-key-of-2025-ada-standards/ The American Diabetes Association (ADA)’s Standards of Care — 2025 offer new guidance on broader use of continuous glucose monitoring (CGM), use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) beyond weight loss, management of metabolic dysfunction-associated liver disease (MAFLD), plus a strong endorsement for drinking water and much more. The […]
21 Gifts That Medical Students Want This Year
Source link : https://www.newshealth.biz/health-news/21-gifts-that-medical-students-want-this-year/ After working hard all year, medical students deserve a restful break and holiday presents that are both practical and fun. You can help them feel supported and appreciated with a mix of gifts related to their professional career as well as their unique interests. For this list, Medscape Medical News spoke […]
Do GLP-1s Lower VTE Risk in People With Type 2 Diabetes?
Source link : https://www.newshealth.biz/health-news/do-glp-1s-lower-vte-risk-in-people-with-type-2-diabetes/ Glucagon-like peptide 1 (GLP-1) receptor agonists led to a significant reduction in the risk for venous thromboembolism (VTE) among individuals with type 2 diabetes compared with dipeptidyl peptidase 4 (DPP-4) inhibitors, a recent analysis indicated. Overall, GLP-1 agonist use was associated with a 20% reduction in VTE compared with DPP-4 inhibitor […]
Early Oseltamivir Benefits Hospitalized Influenza Patients
Source link : https://www.newshealth.biz/health-news/early-oseltamivir-benefits-hospitalized-influenza-patients/ TOPLINE: Early treatment with oseltamivir on the same day as hospital admission was associated with fewer severe clinical outcomes, such as worsening pulmonary disease, need for invasive ventilation, organ failure, and in-hospital death in adults hospitalized with influenza. METHODOLOGY: The 2018 guidelines from the Infectious Disease Society of America recommend prompt […]
How Do Rheumatology PAs Stand Out Among Their Peers?
Source link : https://www.newshealth.biz/health-news/how-do-rheumatology-pas-stand-out-among-their-peers/ TOPLINE: In recent years, the number of physician assistants (PAs) practicing in rheumatology has steadily increased, with most of them being women, working in office-based private practices, and engaging more in telemedicine services; they also report higher job satisfaction and lower burnout symptom rates than their peers in other specialties. METHODOLOGY: […]
Vertebral Fractures and Myeloma: Link Is Questionable
Source link : https://www.newshealth.biz/health-news/vertebral-fractures-and-myeloma-link-is-questionable/ SAN DIEGO — Incidentally discovered vertebral fractures are common on scans in the general population, while the absolute risk for multiple myeloma (MM) in those with such fractures is “quite modest,” according to findings in a Danish cohort of more than 9000 patients. The findings suggest that evaluation for underlying MM […]
Meds Fail to Improve Survival in Comatose Cardiac Arrest
Source link : https://www.newshealth.biz/health-news/meds-fail-to-improve-survival-in-comatose-cardiac-arrest/ TOPLINE: Compared with placebo or standard care, steroids, coenzyme Q10, and thiamine fail to reduce mortality rates in comatose survivors of cardiac arrest. METHODOLOGY: This meta-analysis included 45 randomized clinical trials (5800 patients) analyzing 30 different drugs that were categorized as supportive drugs (10 studies), neuroprotective agents (19 studies), and anti-inflammatory/antioxidants […]
Carer’s Allowance overpayment debt rises to £250m
Source link : https://www.newshealth.biz/health-news/carers-allowance-overpayment-debt-rises-to-250m/ Outstanding debt from Carer’s Allowance overpayments rose to more than £250m last year, according to the government’s spending watchdog. The National Audit Office (NAO) said the figure had increased by £100m since 2018/19. Charity Carers UK said the report was “further evidence of a broken system that is failing unpaid carers”. […]
‘I went in for a tackle and heard my neck snap’
Source link : https://www.newshealth.biz/health-news/i-went-in-for-a-tackle-and-heard-my-neck-snap/ Luke Orton was playing in a rugby tournament in 2023 when his life changed forever Luke Orton was playing in a rugby tournament on the Isle of Wight in July 2023 when his life changed forever. “I went in for a tackle and heard my neck snap,” he said. “It sounded […]
Services will close over National Insurance rise, Mencap tells BBC
Source link : https://www.newshealth.biz/health-news/services-will-close-over-national-insurance-rise-mencap-tells-bbc/ BBC Barry and Betty’s service is not under threat, but Mencap fears it will have to close others A leading charity that supports people with learning disabilities says it may be forced to stop running at least 60 of its services as a result of increasing National Insurance costs. Mencap is […]
State ‘Gold Card’ Laws Sound Good — But Are They Working?
Source link : https://www.newshealth.biz/health-news/state-gold-card-laws-sound-good-but-are-they-working/ Have you wished you could be exempt from prior authorizations, especially because your procedures or prescriptions are almost always approved? That’s the idea behind “gold card” laws some states have implemented, but the laws have not always worked out quite the way supporters have envisioned. Take Texas, for example. Under that […]
Generous Blood Transfusions Not Beneficial for Some With Burst Brain Aneurysms
Source link : https://www.newshealth.biz/health-news/generous-blood-transfusions-not-beneficial-for-some-with-burst-brain-aneurysms/ For people with aneurysmal subarachnoid hemorrhage and anemia, there was no significant neurological benefit from getting red blood cell transfusions more liberally, the SAHARA randomized trial showed. Between a liberal transfusion strategy (mandatory transfusion at a hemoglobin cutoff of ≤10 g/dL) and a restrictive strategy (optional transfusion at a hemoglobin level […]
USPSTF Plans Changes to Cervical Cancer Screening Recommendations
Source link : https://www.newshealth.biz/health-news/uspstf-plans-changes-to-cervical-cancer-screening-recommendations/ The U.S. Preventive Services Task Force (USPSTF) plans to add self-collected human papillomavirus (HPV) testing to its recommendations for cervical cancer screening, among other changes. Task Force Chair Wanda Nicholson, MD, MPH, MBA, of the Milken Institute School of Public Health and George Washington University School of Medicine in Washington D.C., […]
More Beans, Less Red Meat: Nutritionists Weigh in on U.S. Dietary Guidelines
Source link : https://www.newshealth.biz/health-news/more-beans-less-red-meat-nutritionists-weigh-in-on-u-s-dietary-guidelines/ Americans should eat more beans, peas, and lentils and cut back on red and processed meats and starchy vegetables, all while continuing to limit added sugars, sodium, and saturated fat. That’s the advice released Tuesday by an expert panel of nutritionists charged with counseling the U.S. government about the 2025 edition […]
Some Kratom Products Contain Lead at Dangerous Levels for Children
Source link : https://www.newshealth.biz/health-news/some-kratom-products-contain-lead-at-dangerous-levels-for-children/ NEW ORLEANS — A large portion of products made with the herbal supplement kratom contained more lead than is safe for children and women of child-bearing potential to consume in a day, even at low doses, a review of three independent assessments found. At the lowest kratom dose of 3 g, […]
Brain Aging Biomarkers; Midlife Anxiety and Dementia Risk; Who Chose Assisted Dying?
Source link : https://www.newshealth.biz/health-news/brain-aging-biomarkers-midlife-anxiety-and-dementia-risk-who-chose-assisted-dying/ Researchers identified 13 proteins that predicted how quickly or slowly a person’s brain aged. (Nature Aging) Midlife anxiety was common decades before people developed dementia, the Norwegian HUNT study showed. (Alzheimer’s & Dementia) Investigational tavapadon met its primary endpoint in a flexible dosing phase III trial of Parkinson’s disease, showing improvements […]
HEARTS Act Gets Senate Vote; New Myocarditis Classes; Aftermath of PAD Device Scare
Source link : https://www.newshealth.biz/health-news/hearts-act-gets-senate-vote-new-myocarditis-classes-aftermath-of-pad-device-scare/ The office of Senate Majority Leader Chuck Schumer (D-N.Y.) said that this week he will bring the HEARTS Act, the bipartisan legislation to equip schools with automatic external defibrillators and provide CPR training to laypeople, to the Senate floor for a vote on it becoming law. A novel four-stage myocarditis classification […]
Arrhythmia Risk of Lamotrigine Questioned by Observational Data
Source link : https://www.newshealth.biz/health-news/arrhythmia-risk-of-lamotrigine-questioned-by-observational-data/ LOS ANGELES — The FDA’s warning about arrhythmia risk with lamotrigine (Lamictal) based on in vitro data wasn’t borne out in observational cohorts of people with epilepsy, although the risk did appear significant in people with bipolar disease. The difference in findings presented at the American Epilepsy Society (AES) annual meeting […]
Transplantation Fails to Improve Survival in Mantle Cell Lymphoma
Source link : https://www.newshealth.biz/health-news/transplantation-fails-to-improve-survival-in-mantle-cell-lymphoma/ SAN DIEGO — Patients with mantle cell lymphoma (MCL) and undetectable minimal residual disease (uMRD) after induction therapy did not live longer if they underwent hematopoietic cell transplantation (HCT), a randomized trial showed. After a median follow-up of 2.7 years, patients treated with rituximab (Rituxan) and transplantation had a 3-year overall […]
Half-Truths, Big Risks: The Dangers of an Incomplete Medical History
Source link : https://www.newshealth.biz/health-news/half-truths-big-risks-the-dangers-of-an-incomplete-medical-history/ Bitterman is an orthopedic surgeon. Honesty is the lifeblood of the doctor-patient relationship. Without it, even the most skilled physician is working with one hand tied behind their back. I learned this firsthand with a patient who sought elective surgery for a toe deformity. She withheld two crucial facts: she smoked […]
Benefits of Transplant for Pediatric Sickle Cell Disease Add Up a Decade Later
Source link : https://www.newshealth.biz/health-news/benefits-of-transplant-for-pediatric-sickle-cell-disease-add-up-a-decade-later/ SAN DIEGO — Kids with sickle cell disease who underwent allogeneic stem cell transplantation (allo-SCT) had fewer serious disease complications along with better quality-of-life and cognitive outcomes a decade later, updated findings from a French trial showed. The prospective study involved 67 children with a history of abnormal cerebral velocities receiving […]
Masking Policies Show Clear Impact on Hospital-Onset Respiratory Infections
Source link : https://www.newshealth.biz/health-news/masking-policies-show-clear-impact-on-hospital-onset-respiratory-infections/ In this exclusive MedPage Today video, Theodore Pak, MD, PhD, of Harvard Medical School in Boston, discusses the findings from a study that examined how changes in masking and testing policies in hospitals influenced rates of respiratory viral infections, including COVID-19, influenza, and respiratory syncytial virus (RSV), during the 2023-2024 season. […]
What Happened to the Canadian Teen Who Became Critically Ill With H5N1 Bird Flu?
Source link : https://www.newshealth.biz/health-news/what-happened-to-the-canadian-teen-who-became-critically-ill-with-h5n1-bird-flu/ Canadian public health officials closed their investigation into the teenager who became critically ill with the H5N1 bird flu virus, with no source of infection identified. It’s not clear whether the teenager recovered or was released from the hospital. Andy Watson, director of communications for the Office of the Provincial Health […]
Lentiviral Gene Therapy Shows Promise in Severe Hemophilia A
Source link : https://www.newshealth.biz/health-news/lentiviral-gene-therapy-shows-promise-in-severe-hemophilia-a/ SAN DIEGO — Results from a small single-center study showed that treatment with a gene therapy involving the use of lentiviral vector-transduced autologous hematopoietic stem cells (HSCs) increased factor VIII levels in patients with severe hemophilia A. Among five patients, the median factor VIII activity level from 4 weeks until the […]
I Am Torn: Grappling With the Killing of UnitedHealthcare’s CEO
Source link : https://www.newshealth.biz/health-news/i-am-torn-grappling-with-the-killing-of-unitedhealthcares-ceo/ Young is a family medicine physician and nocturnist. I am torn. I have the devil whispering in one ear, telling me to join with the masses hailing the murder of UnitedHealthcare CEO Brian Thompson and shouting that he had it coming to him. And I have the angel speaking in my […]
Alecensa (alectinib) Offers Hope for Certain Patients With ALK Positive NSCLC
Source link : https://www.newshealth.biz/health-news/alecensa-alectinib-offers-hope-for-certain-patients-with-alk-positive-nsclc/ When Matt was diagnosed with ALK-positive (ALK+) metastatic non-small cell lung cancer (mNSCLC), his world turned upside down. It’s a moment that many patients like Matt dread — the words “you have cancer” hang in the air, bringing with it waves of fear and uncertainty. For Matt, a Stage 4 diagnosis […]
Year in Review: Chronic Lymphocytic Leukemia
Source link : https://www.newshealth.biz/health-news/year-in-review-chronic-lymphocytic-leukemia/ Developments in chronic lymphocytic leukemia (CLL) this year included the first CAR T-cell therapy approval for the chronic blood cancer, potential treatments for Richter transformation, and investigations into triplet regimens. First CAR-T Approved for CLL In March, the FDA granted accelerated approval to lisocabtagene maraleucel (liso-cel, Breyanzi) for pretreated CLL or […]
Suspect in UnitedHealthcare Killing Wrote ‘Parasites Simply Had it Coming’
Source link : https://www.newshealth.biz/health-news/suspect-in-unitedhealthcare-killing-wrote-parasites-simply-had-it-coming/ Police arrested a “strong person of interest” Monday in the brazen Manhattan killing of UnitedHealthcare’s CEO after a quick-thinking McDonald’s employee in Pennsylvania alerted authorities to a customer who was found with a weapon and writings linking him to the ambush. The 26-year-old man had a gun believed to be the […]
Novel Drug Fails for Two Rare Seizure Disorders
Source link : https://www.newshealth.biz/health-news/novel-drug-fails-for-two-rare-seizure-disorders/ LOS ANGELES — The novel agent soticlestat flopped in a pair of phase III trials for rare seizure disorders, researchers reported here. Among Dravet syndrome patients in the SKYLINE trial, the median change from baseline in convulsive seizure frequency over the full treatment period was -22.16% with soticlestat and -8.64% with […]
AI Screening of Home Videos Proves Accurate for Infantile Seizure Detection
Source link : https://www.newshealth.biz/health-news/ai-screening-of-home-videos-proves-accurate-for-infantile-seizure-detection/ LOS ANGELES — An artificial intelligence (AI) model accurately detected and ruled out infantile epileptic spasm syndrome in videos captured by family, a study showed. The model had an area under the receiver-operating-curve (AUC) of 0.96, with 82% sensitivity and 90% specificity, reported Gadi Miron, MD, of Charité-Universitätsmedizin Berlin in Germany, […]
Empathetic Phone Calls Help Vulnerable Diabetes Patients Lower HbA1c
Source link : https://www.newshealth.biz/health-news/empathetic-phone-calls-help-vulnerable-diabetes-patients-lower-hba1c/ Empathy-oriented phone calls from laypersons helped patients with uncontrolled diabetes improve glycemic control, a parallel-arm superiority trial found. Among 260 participants, those who received calls from community-hired laypeople decreased their HbA1c from 10% to 9.3% by 6 months. Meanwhile, HbA1c in the usual care group held steady from 9.8% to 9.7%, […]
‘Parasites Simply Had it Coming’; Second U.S. Kid With Bird Flu? Rx for Solar Power
Source link : https://www.newshealth.biz/health-news/parasites-simply-had-it-coming-second-u-s-kid-with-bird-flu-rx-for-solar-power/ Note that some links may require registration or subscription. Luigi Mangione, a 26-year-old suspect in last week’s killing of UnitedHealthcare CEO Brian Thompson, was charged with murder in New York. A three-page, handwritten document found in his possession included a line that “these parasites simply had it coming,” a law enforcement […]
Women Who Revolutionized Modern Medicine
Source link : https://www.newshealth.biz/health-news/women-who-revolutionized-modern-medicine/ In the winter semester of 2023, there were 113,383 students enrolled in medical programs in Germany, 73,244 of whom were women. This equates to nearly 65%, a remarkable figure considering that women were only granted access to universities in 1899. The rationale for their exclusion was the belief that a woman’s […]
The Multipronged Problem of Candida auris
Source link : https://www.newshealth.biz/health-news/the-multipronged-problem-of-candida-auris/ Candida auris, a yeast-like fungus, is spreading globally, increasing the urgency for enhanced surveillance, new therapies, and more antimicrobial stewardship to combat its multidrug-resistant strains. Since its discovery in 2009, Candida auris has been found in more than 50 countries across six continents, including Asia, Africa, and the Americas, according to […]
Clopidogrel Tops Aspirin Post-PCI, Even in High-Risk Cases
Source link : https://www.newshealth.biz/health-news/clopidogrel-tops-aspirin-post-pci-even-in-high-risk-cases/ TOPLINE: The beneficial effect of clopidogrel monotherapy over aspirin monotherapy in patients who underwent percutaneous coronary intervention (PCI) and remained event free for 6-18 months on dual antiplatelet therapy (DAPT) is consistent, regardless of bleeding risk or PCI complexity, according to a post hoc analysis of the HOST-EXAM trial. METHODOLOGY: The […]
Fertility Preservation in SCD: Women Have More Complications
Source link : https://www.newshealth.biz/health-news/fertility-preservation-in-scd-women-have-more-complications/ SAN DIEGO — Significant complications were common in female patients with sickle cell disease (SCD) who underwent fertility preservation (FP) procedures, and 13% required multiple retrieval cycles, a five-center retrospective study found. Of 46 patients with SCD, complications occurred in 25 of 55 controlled ovarian hyperstimulation cycles, including 29 vaso-occlusive episodes […]
Sleep Apnea Linked to Heightened Mortality in Epilepsy
Source link : https://www.newshealth.biz/health-news/sleep-apnea-linked-to-heightened-mortality-in-epilepsy/ LOS ANGELES — Individuals with both uncontrolled epilepsy and sleep apnea are at significantly higher risk for mortality than those with epilepsy alone, according to a new analysis of over 2 million patient-years drawn from the Komodo Health Claims Database. “A 10-year-old with uncontrolled central sleep apnea is about 200 times […]
AI Tool Predicts Progression From MCI to AD: What to Know
Source link : https://www.newshealth.biz/health-news/ai-tool-predicts-progression-from-mci-to-ad-what-to-know/ An estimated 14 million older adults in the United States live with mild cognitive impairment (MCI). While many will never progress to dementia — experiencing stable or even improved cognitive function — predicting the likely course of the condition has remained elusive. That is, until now. Earlier this year, the US […]
Leaded Gas Exposure Tied to Millions of Mental Illness Cases
Source link : https://www.newshealth.biz/health-news/leaded-gas-exposure-tied-to-millions-of-mental-illness-cases/ Childhood exposure to leaded gasoline via car exhaust over the past 75 years is linked to 151 million excess cases of psychiatric disorders in the United States, new research suggested. The data revealed that the group most heavily exposed to lead — individuals born between 1966 and 1986, commonly known as […]
Extended Results Confirm Standard of Care for DLBCL
Source link : https://www.newshealth.biz/health-news/extended-results-confirm-standard-of-care-for-dlbcl/ SAN DIEGO — Patients with diffuse large B-cell lymphoma (DLBCL) continue to show superior progression-free survival at 5 years with first-line pola-R-CHP compared with the R-CHOP regimen, according to updated results of the phase 3 POLARIX study. These findings “confirm pola-R-CHP as the standard of care for patients with previously untreated […]
How Are Patients Managing Intermediate-Risk Prostate Cancer?
Source link : https://www.newshealth.biz/health-news/how-are-patients-managing-intermediate-risk-prostate-cancer/ TOPLINE: The use of active surveillance or watchful waiting increased by more than twofold overall between 2010 and 2020 among patients with intermediate-risk prostate cancer. METHODOLOGY: Current guidelines support active surveillance or watchful waiting for select patients with intermediate-risk prostate cancer. These observation strategies may help reduce the adverse effects associated […]
Smart Mattress to Reduce SUDEP?
Source link : https://www.newshealth.biz/health-news/smart-mattress-to-reduce-sudep/ LOS ANGELES — A mattress designed to detect seizures in individuals with epilepsy who are lying face down and quickly reposition them onto their side could significantly reduce the risk for sudden unexpected death in epilepsy (SUDEP), says one of the experts involved in its development. When used along with a […]
TIVA Enables Earlier Facial Nerve Monitoring in Ear Surgery
Source link : https://www.newshealth.biz/health-news/tiva-enables-earlier-facial-nerve-monitoring-in-ear-surgery/ TOPLINE: Total intravenous anesthesia (TIVA) enables earlier intraoperative monitoring of facial nerve activity than sevoflurane anesthesia during ear surgery, with reduced patient-ventilator dyssynchrony and fewer requirements for postoperative antiemetics. METHODOLOGY: Researchers evaluated the difference in the timeliness of intraoperative monitoring of facial nerve activity during ear surgery with TIVA vs sevoflurane […]
Smoking Linked to More Genetic Havoc in MDS
Source link : https://www.newshealth.biz/health-news/smoking-linked-to-more-genetic-havoc-in-mds/ SAN DIEGO — A new study linked longer duration and deeper intensity of tobacco smoking to more genetic mutations in myelodysplastic syndromes (MDSs), a group of bone marrow cancers that are similar to acute myeloid leukemia. The prospective National MDS Natural History Study evaluated 1898 patients with recently diagnosed or suspected […]
More Biologics Breaking Through for COPD
Source link : https://www.newshealth.biz/health-news/more-biologics-breaking-through-for-copd/ New biologic drugs for chronic obstructive pulmonary disease (COPD) are finally here, said Stephen Rennard, MD, in a presentation in a session on new drugs at the 2024 GOLD International COPD Conference. The inflammatory pathways associated with COPD are diverse and offer a range of potential targets for biologics, said Rennard, […]
Malpractice in the Age of AI
Source link : https://www.newshealth.biz/health-news/malpractice-in-the-age-of-ai/ Instead of sitting behind a laptop during patient visits, the pediatrician directly faces the patient and parent, relying on an ambient artificial intelligence (AI) scribe to capture the conversation for the electronic health record (EHR). A geriatrician doing rounds at the senior living facility plugs each patient’s medications into an AI […]
Self-Care Can Elevate Quality of Life in Chronic Diseases
Source link : https://www.newshealth.biz/health-news/self-care-can-elevate-quality-of-life-in-chronic-diseases/ TOPLINE: Self-care preparedness is positively associated with improved health-related quality of life (HRQOL) in patients with chronic conditions over 36 months, and patients who enhance their self-care preparedness experience better QOL outcomes. METHODOLOGY: A secondary analysis of a randomized controlled trial conducted in Finland from 2017 to 2021 aimed to analyze […]
Does Acalabrutinib Fit Into Frontline MCL Therapy?
Source link : https://www.newshealth.biz/health-news/does-acalabrutinib-fit-into-frontline-mcl-therapy/ For younger, fit patients with mantle cell lymphoma (MCL), adding the Bruton’s tyrosine kinase (BTK) inhibitor acalabrutinib to standard induction therapy with bendamustine/rituximab followed by cytarabine/rituximab adds toxicity without improving efficacy, results of the phase 2 ECOG-ACRIN EA4181 trial indicate. However, treating patients with bendamustine/rituximab plus acalabrutinib might be preferred to […]
Canadian Bill Would Require Interoperable Health IT
Source link : https://www.newshealth.biz/health-news/canadian-bill-would-require-interoperable-health-it/ New legislation would require health information technology (IT) to be interoperable across the country, thus allowing patients and healthcare providers to access health data from different electronic medical records. The Connected Care for Canadians Act, also known as Bill C-72, says, “data blocking by a health information technology vendor is prohibited.” […]
Which States Have the Most Outstanding Hospitals for Maternity Care?
Source link : https://www.newshealth.biz/health-news/which-states-have-the-most-outstanding-hospitals-for-maternity-care/ Among the 414 facilities that earned top marks on the 2024 “Best Hospitals for Maternity Care” list from U.S. News & World Report, 17 states had 10 or more high-performing hospitals. California had the most, followed by New Jersey, and Texas. Rhode Island and South Dakota did not have any facilities […]
APA Updates Guidance on Borderline Personality Disorder
Source link : https://www.newshealth.biz/health-news/apa-updates-guidance-on-borderline-personality-disorder/ For the first time since 2001, the American Psychiatric Association (APA) has updated its clinical practice guideline on borderline personality disorder (BPD). The new guideline is “quite substantial and really serves as a rich textbook of the literature, about borderline personality disorder that any clinician would find very valuable,” John Oldham, […]
One in Six Adults With Asthma Didn’t Adhere to Meds Due to Cost
Source link : https://www.newshealth.biz/health-news/one-in-six-adults-with-asthma-didnt-adhere-to-meds-due-to-cost/ Despite a declining trend, the number of adults in the U.S. who say they did not adhere to their asthma treatment because of costs remains high, according to an observational study. From 2011-2022, the prevalence of cost-related non-adherence decreased from 23.2% to 13.1%. However, about one in six adults with asthma […]
‘My autistic son had no safety net when in crisis’
Source link : https://www.newshealth.biz/health-news/my-autistic-son-had-no-safety-net-when-in-crisis/ Family handout Declan Morrison’s father said the 26-year-old had enjoyed listening to birdsong at twilight The family of a man who died after he repeatedly banged his head against a wall in a mental health suite said there was no “safety net” for people with their son’s needs. Declan Morrison, 26, […]
Procalcitonin Confirmed as Good Gauge for Window of Sepsis Antibiotics
Source link : https://www.newshealth.biz/health-news/procalcitonin-confirmed-as-good-gauge-for-window-of-sepsis-antibiotics/ For critically ill patients on antibiotics for suspected sepsis, monitoring one biomarker safely shortened the course of these medications in the ADAPT-Sepsis randomized trial. Daily assessment of procalcitonin (PCT), rather than standard care alone, led to patients spending significantly less time on antibiotics cumulatively in the first 28 days (9.8 days […]
Who Is Luigi Mangione, the ‘Person of Interest’ in the UnitedHealthcare Murder?
Source link : https://www.newshealth.biz/health-news/who-is-luigi-mangione-the-person-of-interest-in-the-unitedhealthcare-murder/ Police arrested a 26-year-old man on Monday in the Manhattan killing of UnitedHealthcare’s CEO after they say a Pennsylvania McDonald’s worker alerted authorities to a customer who resembled the suspected gunman. The suspect, identified by police as Luigi Nicholas Mangione, had a gun believed to be the one used in Wednesday’s […]
How Measles, Whooping Cough, and Worse Could Roar Back on RFK Jr.’s Watch
Source link : https://www.newshealth.biz/health-news/how-measles-whooping-cough-and-worse-could-roar-back-on-rfk-jr-s-watch/ The availability of safe, effective COVID vaccines less than a year into the pandemic marked a high point in the 300-year history of vaccination, seemingly heralding an age of protection against infectious diseases. Now, after backlash against public health interventions culminated in President-elect Donald Trump’s nominating Robert F. Kennedy Jr., the […]
Modernizing the Electronic Health Record
Source link : https://www.newshealth.biz/health-news/modernizing-the-electronic-health-record/ Fred Pelzman is an associate professor of medicine at Weill Cornell, and has been a practicing internist for nearly 30 years. He is medical director of Weill Cornell Internal Medicine Associates. In the evolving world of healthcare, what should the medical record — and in particular, the 21st century progress note […]
Hydroxyurea Shows Some Benefits in Milder Sickle Cell Disease
Source link : https://www.newshealth.biz/health-news/hydroxyurea-shows-some-benefits-in-milder-sickle-cell-disease/ SAN DIEGO — Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a Ghanaian randomized phase II trial showed. Hematologic DLTs — mostly mild and transient — occurred in 33% of patients taking hydroxyurea […]
Rheumatoid Arthritis Boosts Risk for Heart Failure, but Not Every Kind
Source link : https://www.newshealth.biz/health-news/rheumatoid-arthritis-boosts-risk-for-heart-failure-but-not-every-kind/ Rates of heart failure with preserved ejection fraction (HFpEF) were doubled in patients with rheumatoid arthritis (RA) relative to other people of the same age and sex, researchers found. On the other hand, risk for heart failure with reduced ejection fraction (HFrEF) wasn’t significantly higher in the RA patients, according to […]
Use of Depression Treatments Lower for Teens in States With Parental Consent Laws
Source link : https://www.newshealth.biz/health-news/use-of-depression-treatments-lower-for-teens-in-states-with-parental-consent-laws/ Use of treatment for depression among adolescents was significantly lower in states that mandate caregiver consent for such treatment, according to a cross-sectional study. After adjusting for state-level prevalence estimates of adolescent major depressive episodes, those who experienced an episode in the past year in states with laws prohibiting independent adolescent […]
Racial Diversity Lacking in Epilepsy Genetics Studies
Source link : https://www.newshealth.biz/health-news/racial-diversity-lacking-in-epilepsy-genetics-studies/ LOS ANGELES — Low racial diversity has limited genome-wide association studies (GWAS) in epilepsy, researchers found, with implications for prognostication and management decisions. Across all published GWAS on epilepsy, 71.5% of tested individuals were of European ancestry, 14.3% East Asian, 0.5% African, and 13.7% without reported ancestry. None of the participants […]
Disability Redefines ‘Ability’ in the Medical Profession
Source link : https://www.newshealth.biz/health-news/disability-redefines-ability-in-the-medical-profession/ Lazarus is an adjunct professor of psychiatry. Last month, Elton John told Good Morning America‘s Robin Roberts that he has lost significant vision in his right eye due to an infection and is unsure whether he can record an album again. Paul Simon recently revealed that hearing loss has caused him […]
Stopping MS Drugs Leads to Inflammatory Activity in Some Stable Patients
Source link : https://www.newshealth.biz/health-news/stopping-ms-drugs-leads-to-inflammatory-activity-in-some-stable-patients/ Nearly one in five stable MS patients developed significant radiological inflammation after stopping first-line treatment. The median time to disease activity after discontinuing treatment was 12 months. The trial was terminated early because recurrent disease activity exceeded predefined limits. Significant radiological inflammation emerged in nearly one in five stable multiple sclerosis […]
Fixed-Duration Oral Doublet for Fit CLL Wins in Frontline Setting
Source link : https://www.newshealth.biz/health-news/fixed-duration-oral-doublet-for-fit-cll-wins-in-frontline-setting/ SAN DIEGO — A fixed-duration oral combination significantly reduced the risk of disease progression or death compared with chemoimmunotherapy in fit patients with previously untreated chronic lymphocytic leukemia (CLL), the phase III AMPLIFY trial showed. The progression-free survival (PFS) rate at 3 years reached 76.5% with acalabrutinib (Calquence) plus venetoclax (Venclexta), […]
Person of Interest in CEO’s Killing in Police Custody
Source link : https://www.newshealth.biz/health-news/person-of-interest-in-ceos-killing-in-police-custody/ A man with a gun thought to be similar to the one used in the killing of UnitedHealthcare CEO Brian Thompson was taken into police custody Monday for questioning in Pennsylvania, a law enforcement official told the Associated Press. The man is being held near Altoona, Pennsylvania, about 233 miles (375 […]
Women With Epilepsy Often Remain Unaware of Medication’s Pregnancy Risks
Source link : https://www.newshealth.biz/health-news/women-with-epilepsy-often-remain-unaware-of-medications-pregnancy-risks/ LOS ANGELES — Many women of reproductive age who were taking antiseizure medication didn’t fully understand its implications for pregnancy or have care that aligned with their reproductive goals, researchers found. Of 107 women ages 18-49, 67.3% answered at least one question incorrectly about the teratogenicity of their antiseizure medication or […]
Could a Hypertension Drug Protect Against Post-Stroke Epilepsy?
Source link : https://www.newshealth.biz/health-news/could-a-hypertension-drug-protect-against-post-stroke-epilepsy/ LOS ANGELES — Use of angiotensin receptor blockers (ARBs) was linked to a lower risk of epilepsy after an acute ischemic stroke, according to an observational study. Among hypertensive patients, ARB use was the only factor significantly associated with onset of post-stroke epilepsy after multivariate adjustment, reported Giacomo Evangelista, MD, of […]
Treatment of Smoldering Myeloma Cuts Progression Rate in Half
Source link : https://www.newshealth.biz/health-news/treatment-of-smoldering-myeloma-cuts-progression-rate-in-half/ SAN DIEGO — The risk of progression from smoldering multiple myeloma to symptomatic disease decreased by 50% in patients treated with the anti-CD38 monoclonal antibody daratumumab (Darzalex), according to a study reported here. The progression-free survival (PFS) rate at 5 years improved from 40.8% with active monitoring and no disease-specific treatment […]
Thirteen proteins in your blood could reveal the age of your brain
Source link : https://www.newshealth.biz/health-news/thirteen-proteins-in-your-blood-could-reveal-the-age-of-your-brain/ Researchers trained an artificial intelligence model to gauge people’s ages from their brain scans laboratory/Alamy The abundance of 13 proteins in your blood seems to be a strong indicator of how rapidly your brain is ageing. This suggests that blood tests could one day help people track and even boost their […]