Two Lung Cancer Drugs Recommended by EMA
Source link : https://www.newshealth.biz/health-news/two-lung-cancer-drugs-recommended-by-ema/ The European Medicines Agency (EMA) recommended eight medicines for approval this month, including two cancer drugs for treating non-small cell lung cancer (NSCLC). Repotrectinib for Advanced Cancers The regulatory body’s Committee for Medicinal Products for Human Use (CHMP) supported granting a conditional marketing authorization for repotrectinib (Augtyro). The drug is intended […]
Leqembi Okayed for Subset of Early Alzheimer’s Patients
Source link : https://www.newshealth.biz/health-news/leqembi-okayed-for-subset-of-early-alzheimers-patients/ The European Medicines Agency’s (EMA’s) Committee for Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for Leqembi (lecanemab) to treat mild cognitive impairment and early Alzheimer’s disease, following a re-examination of the clinical data. The recommendation is only for patients who have one or no copies of the […]
Primary Biliary Cholangitis Incidence and Prevalence Growing
Source link : https://www.newshealth.biz/health-news/primary-biliary-cholangitis-incidence-and-prevalence-growing/ Primary biliary cholangitis (PBC) has typically been considered a rare condition, with a pooled global estimated incidence of two per 100,000 people per year and an estimated prevalence of 15 per 100,000 people per year. But both its incidence and prevalence have been increasing, and it’s the most common cholestatic disease […]
Eyenovia to Discontinue Late-stage Study for Eye Drug
Source link : https://www.newshealth.biz/health-news/eyenovia-to-discontinue-late-stage-study-for-eye-drug/ (Reuters) -Eyenovia said on Friday it would terminate a late-stage study for its experimental drug-device combination to treat an eye disease after failing the main goal of slowing the progression of the condition. The disease, called pediatric progressive myopia, causes near-sightedness in early childhood, which worsens as the person grows. An […]
CT Scan and Antibiotic Usage Trends for Diverticulitis
Source link : https://www.newshealth.biz/health-news/ct-scan-and-antibiotic-usage-trends-for-diverticulitis/ TOPLINE: Despite lower admission rates, the incidence of diverticulitis has increased over 8 years in the United States, along with an increased use of CT scans and a shift to penicillin-based antibiotics, a study found. METHODOLOGY: The researchers conducted a cross-sectional study using data from the Epic Cosmos database of 186,138,130 […]
Why Topical Retinoids Are Key to Every Acne Regimen
Source link : https://www.newshealth.biz/health-news/why-topical-retinoids-are-key-to-every-acne-regimen/ LAS VEGAS — No matter which treatment regimen is recommended for patients with acne, it should always include a topical retinoid, according to dermatologist Hilary Baldwin, MD. Hilary Baldwin, MD Patients with successfully treated acne typically use an average of 2.53 different medications, Baldwin, director of the Acne Treatment & Research […]
From Mexico City to the Heights of Leukemia Medicine
Source link : https://www.newshealth.biz/health-news/from-mexico-city-to-the-heights-of-leukemia-medicine/ If the name of leukemia specialist Jorge Cortes, MD, appears any more often in PubMed, they’ll need to name a wing after him. Jorge Cortes, MD Over 30 years, Cortes has led or co-authored hundreds of studies, including many trials of landmark drugs to treat chronic myeloid leukemia (CML). His work […]
More Than 800 Million People Worldwide Have Diabetes
Source link : https://www.newshealth.biz/health-news/more-than-800-million-people-worldwide-have-diabetes/ TOPLINE: Since 1990, the largest increase in diabetes prevalence has occurred in low-income and middle-income countries, whereas improvements in treatment have been greatest in high-income and industrialized nations and some emerging economies, especially in Latin America. These trends have widened the global gap in diabetes prevalence and treatment, with an increasing […]
PCOS Linked to Reduced Fertility and Later Childbirth
Source link : https://www.newshealth.biz/health-news/pcos-linked-to-reduced-fertility-and-later-childbirth/ TOPLINE: Women with polycystic ovary syndrome (PCOS) have 26% higher nulliparity rates and give birth at more advanced ages despite similar family aspirations and higher rates of fertility treatment. Later PCOS diagnosis is associated with double the rate of advanced maternal age at childbirth. METHODOLOGY: A prospective cohort study followed 14,247 […]
Do Antibiotics Worsen Lung Immunity During Flu?
Source link : https://www.newshealth.biz/health-news/do-antibiotics-worsen-lung-immunity-during-flu/ TOPLINE: Antibiotic use during influenza infection increases lung eosinophils, impairing immunity against secondary bacterial pneumonia. This study highlights the detrimental effects of antibiotics on lung health during viral infections. METHODOLOGY: Researchers conducted a murine model study to evaluate the impact of antibiotic use during influenza infection on lung immunity. Mice were […]
Nirsevimab Resistance Mutations Rare in RSV, Study Shows
Source link : https://www.newshealth.biz/health-news/nirsevimab-resistance-mutations-rare-in-rsv-study-shows/ Nirsevimab (Beyfortus), an antibody targeting respiratory syncytial virus (RSV), is indicated for newborns and infants to prevent bronchiolitis. Available since September 2023, its widespread use may lead to resistance mutations. However, according to the French POLYRES study on prospective monitoring of nirsevimab, published recently in The Lancet Infectious Diseases, these mutations […]
One-Stop Shops for Patients With BRCA Mutations
Source link : https://www.newshealth.biz/health-news/one-stop-shops-for-patients-with-brca-mutations/ In 2012, a $25 million donation established the Basser Center for BRCA at the University of Pennsylvania, Philadelphia. For years, the Basser Center was touted as the only comprehensive center for the research, treatment, and prevention of cancers related to the BRCA1 and BRCA2 genetic mutations, which carry associations with cancers […]
Air Pollution Raises Risk for Spontaneous Preterm Birth
Source link : https://www.newshealth.biz/health-news/air-pollution-raises-risk-for-spontaneous-preterm-birth/ TOPLINE: Exposure to fine particulate matter (PM2.5) during pregnancy is associated with an increased risk for spontaneous preterm birth, with peak vulnerability in the second trimester. Lower socioeconomic status, limited green space exposure, and extreme heat amplify this risk, whereas living around more trees provides protective effects. METHODOLOGY: The researchers conducted […]
Managing Diabetes and Dementia in Long-Term Care
Source link : https://www.newshealth.biz/health-news/managing-diabetes-and-dementia-in-long-term-care/ VANCOUVER, British Columbia — Conditions like diabetes and dementia are common in patients who are admitted to long-term care facilities, but aggressive management of these conditions in long-term care residents is not recommended, according to a presentation given at the Family Medicine Forum (FMF) 2024. Hospitalizations for hypoglycemia are risky for […]
Davina McCall to have surgery for rare brain tumour
Source link : https://www.newshealth.biz/health-news/davina-mccall-to-have-surgery-for-rare-brain-tumour/ Davina McCall is having surgery to remove a brain tumour, she has revealed. The TV presenter posted a video on Instagram to say she had been diagnosed with a rare type of benign tumour called a colloid cyst. A benign tumour is not cancerous, but such cysts tend to grow slowly, […]
When Patients Don’t Show Up
Source link : https://www.newshealth.biz/health-news/when-patients-dont-show-up/ For decades, no-show patients have proven to be a costly problem for physicians. In fact, missed appointments lead to a staggering $150 billion impact on the US healthcare system annually. The reasons patients opt out of appointments are as individual as the patient and include concerns about healthcare costs, long wait […]
‘Inevitable’ That AI Will Be Integrated Into Medical Care
Source link : https://www.newshealth.biz/health-news/inevitable-that-ai-will-be-integrated-into-medical-care/ Medscape’s 2024 survey of over 5000 practicing clinicians from six European countries has showed there is more enthusiasm than apprehension about the use of artificial intelligence (AI) in medicine. However, many doctors have reasonable concerns, and the survey reveals a worrying knowledge gap among physicians. Experts predict that it is inevitable […]
When Is It Best to Quit?
Source link : https://www.newshealth.biz/health-news/when-is-it-best-to-quit/ TOPLINE: Starting smoking cessation treatment within 9 months of a cancer diagnosis was associated with improved survival across various cancer types, with the greatest survival benefit observed among patients who began the process within 6 months of their diagnosis. METHODOLOGY: The 2020 Surgeon General’s report and recent evidence indicate that quitting […]
A New and Early Predictor of Future Dementia?
Source link : https://www.newshealth.biz/health-news/a-new-and-early-predictor-of-future-dementia/ Signs of frailty may signal future dementia more than a decade before cognitive symptoms occur, in new findings that may provide a potential opportunity to identify high-risk populations for targeted enrollment in clinical trials of dementia prevention and treatment. Results of an international study assessing frailty trajectories showed frailty levels notably […]
Not All Women Get the Same Cancer Care
Source link : https://www.newshealth.biz/health-news/not-all-women-get-the-same-cancer-care/ Socioeconomic factors and education levels significantly affect access to cancer screening and best-suited care for women in Europe, according to a recently published report by the European Cancer Organisation (ECO). The report said inequalities in screening and care are prevalent among marginalized communities such as minority ethnic groups and LGBTQ+ people. […]
Frequent ED Visits and Risk for Severe Maternal Morbidity
Source link : https://www.newshealth.biz/health-news/frequent-ed-visits-and-risk-for-severe-maternal-morbidity/ TOPLINE: Pregnant individuals, particularly younger and Hispanic or non-Hispanic Black women, with four or more visits to the emergency department (ED) in the United States are more likely to experience severe maternal morbidity (SMM) at the time of birth. METHODOLOGY: Researchers conducted a cohort study using data from the Massachusetts Pregnancy […]
Larger Study Supports Safety of Tetracyclines During Early Pregnancy
Source link : https://www.newshealth.biz/health-news/larger-study-supports-safety-of-tetracyclines-during-early-pregnancy/ The link between first trimester tetracycline exposure and major congenital malformations (MCMs) was not supported by a large cohort study based on Sweden’s national registers. Incidence of any MCM diagnosed in the first year of life reached 39.75 cases per 1,000 exposed infants versus a similar 38.76 cases per 1,000 unexposed […]
We Cannot Provide Care With Our Hands Tied Behind Our Backs
Source link : https://www.newshealth.biz/health-news/we-cannot-provide-care-with-our-hands-tied-behind-our-backs/ While pledging to “make America healthy again,” President-elect Donald Trump gave former environmental lawyer Robert F. Kennedy Jr. — whose curriculum vitae includes neither scientific background nor a medical degree — carte blanche to “go wild” on health under his administration. These two announcements seem incompatible with each other. Aside from […]
RFK Jr. Selected to Lead HHS
Source link : https://www.newshealth.biz/health-news/rfk-jr-selected-to-lead-hhs/ (MedPage Today) — Donald Trump has nominated Robert F. Kennedy Jr. to be secretary of the Department of Health and Human Services, the president-elect announced. The move is expected to send a jolt through the medical and public health community… Source link : https://www.medpagetoday.com/washington-watch/washington-watch/112913 Author : Publish date : 2024-11-14 21:24:36 […]
Adding HIPEC Boosts Survival in Recurrent Ovarian Cancer
Source link : https://www.newshealth.biz/health-news/adding-hipec-boosts-survival-in-recurrent-ovarian-cancer/ Adding hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery significantly improved overall survival (OS) in women with platinum-sensitive, recurrent epithelial ovarian carcinoma, a phase III randomized trial showed. In over 400 women at first epithelial ovarian cancer recurrence, those who received HIPEC had a median OS of 54.3 months compared with 45.8 […]
First Brain-Delivered Gene Therapy Approved for AADC Deficiency
Source link : https://www.newshealth.biz/health-news/first-brain-delivered-gene-therapy-approved-for-aadc-deficiency/ The FDA granted accelerated approval to eladocagene exuparvovec (Kebilidi) to treat children and adults with aromatic L-amino acid decarboxylase (AADC) deficiency, the agency announced Thursday. The treatment is the first approved gene therapy for AADC deficiency, the FDA said. People with this rare disorder have decreased AADC activity that causes severe […]
First Brain-Delivered Gene Therapy Approved for AADC Deficiency
Source link : https://www.newshealth.biz/health-news/first-brain-delivered-gene-therapy-approved-for-aadc-deficiency/ The FDA granted accelerated approval to eladocagene exuparvovec (Kebilidi) to treat children and adults with aromatic L-amino acid decarboxylase (AADC) deficiency, the agency announced Thursday. The treatment is the first approved gene therapy for AADC deficiency, the FDA said. People with this rare disorder have decreased AADC activity that causes severe […]
First Brain-Delivered Gene Therapy Approved for AADC Deficiency
Source link : https://www.newshealth.biz/health-news/first-brain-delivered-gene-therapy-approved-for-aadc-deficiency/ The FDA granted accelerated approval to eladocagene exuparvovec (Kebilidi) to treat children and adults with aromatic L-amino acid decarboxylase (AADC) deficiency, the agency announced Thursday. The treatment is the first approved gene therapy for AADC deficiency, the FDA said. People with this rare disorder have decreased AADC activity that causes severe […]
Faricimab vs Aflibercept in Diabetic Macular Edema
Source link : https://www.newshealth.biz/health-news/faricimab-vs-aflibercept-in-diabetic-macular-edema/ Intraretinal hyperreflective foci, intraretinal hard exudates, and epiretinal membrane formation were lower after treatment with faricimab (Vabysmo) compared with aflibercept (Eylea) for patients with diabetic macular edema (DME), according to an analysis presented at the American Academy of Ophthalmology meeting. In this exclusive MedPage Today video, Jennifer Lim, MD, of the […]
Weight-loss medications may also ease chronic pain
Source link : https://www.newshealth.biz/health-news/weight-loss-medications-may-also-ease-chronic-pain/ Popular semaglutide-based drugs used for weight loss may reduce chronic and acute pain, which could make them a promising alternative to opioids Source link : https://www.newscientist.com/article/2456295-weight-loss-medications-may-also-ease-chronic-pain/?utm_campaign=RSS%7CNSNS&utm_source=NSNS&utm_medium=RSS&utm_content=health Author : Publish date : 2024-11-14 21:34:00 Copyright for syndicated content belongs to the linked Source. Author : News Health Publish date : 2024-11-14 21:34:00 […]
Debunking Fluoride Misinfo; Mummy Gets CT Scan; Come Quit My NP Job With Me
Source link : https://www.newshealth.biz/health-news/debunking-fluoride-misinfo-mummy-gets-ct-scan-come-quit-my-np-job-with-me/ The following contains links to social media websites including X, TikTok, Instagram, Facebook, and LinkedIn. After Robert F. Kennedy Jr. announced on X that President-elect Donald Trump would push to remove fluoride from drinking water, @epidemiologistkat took to TikTok to dispel misinformation about fluoride and emphasize its health benefits. Ob/gyn Karen […]
Evidence of Resistance to Standard Malaria Therapy for Severe Cases
Source link : https://www.newshealth.biz/health-news/evidence-of-resistance-to-standard-malaria-therapy-for-severe-cases/ Partial resistance to artemisinin, the recommended treatment for Plasmodium falciparum malaria, occurred in Ugandan children with severe disease who were treated with the drug, and some treated patients had recurrence of their infection, according to a small prospective study. Artemisinin partial resistance — defined as a half-life for parasite clearance of […]
Accuracy of Skin Cancer Diagnosis Varies by Physician, Exam Method
Source link : https://www.newshealth.biz/health-news/accuracy-of-skin-cancer-diagnosis-varies-by-physician-exam-method/ The accuracy of skin cancer diagnosis varied by lesion type, physician specialty and experience, and examination method, with the greatest accuracy observed for dermatologists using dermoscopy, according to findings from a systematic review and meta-analysis. Across 100 studies, experienced dermatologists had 5.7-fold higher odds of accurate diagnosis of melanoma using dermoscopy […]
Doctors React to Texas Rule Requiring Them to Ask About Immigration Status
Source link : https://www.newshealth.biz/health-news/doctors-react-to-texas-rule-requiring-them-to-ask-about-immigration-status/ A new Texas rule that requires hospitals to ask patients about immigration status has raised concern about further straining trust between physicians and their patients, according to experts who spoke with MedPage Today. “As a doctor who has chosen to work in safety net hospitals, which are designed to care for […]
SDPA Marks Its 30th Year of Supporting Physician Associates
Source link : https://www.newshealth.biz/health-news/sdpa-marks-its-30th-year-of-supporting-physician-associates/ LAS VEGAS — As Amber Blair, PA-C, delivered her presidential address to members of the Society of Dermatology Physician Associates (SDPA) at its annual fall meeting, she reflected on the growth of the organization since its founding in 1994 by Joe R. Monroe, MPAS, PA. Back then, the organization had just […]
Birth Control and Abortion Pill Requests Have Surged Since Trump Won the Election
Source link : https://www.newshealth.biz/health-news/birth-control-and-abortion-pill-requests-have-surged-since-trump-won-the-election/ Hours after Donald Trump was elected president for the second time, Clayton Alfonso, MD, had two messages from patients seeking to replace their intrauterine devices (IUDs). Over the next few days, three women inquired about getting their tubes tied. All of them said the election was the reason they were making […]
New FDA Rules for TV Drug Ads: Simpler Language and No Distractions
Source link : https://www.newshealth.biz/health-news/new-fda-rules-for-tv-drug-ads-simpler-language-and-no-distractions/ The ever-present TV drug ads showing patients hiking, biking, or enjoying a day at the beach could soon have a different look, as new rules require drugmakers to be clearer and more direct when explaining their medications’ risks and side effects. The FDA spent more than 15 years crafting the guidelines, […]
Alarming Surge in Alcohol-Related Liver Transplants in Younger Adults
Source link : https://www.newshealth.biz/health-news/alarming-surge-in-alcohol-related-liver-transplants-in-younger-adults/ Rates of alcohol-induced liver disease (AILD)-related hospitalizations and liver transplants surged over the past two decades, with particularly steep increases among younger adults in recent years, an analysis of U.S. data showed. From 2005 to 2021, hospitalizations for AILD doubled from 63 to 129 per 100,000 women, while increasing from 187 […]
$13M Award for COVID Vax Refuser; Doc Sentenced for Threats to Blow Up Hospital
Source link : https://www.newshealth.biz/health-news/13m-award-for-covid-vax-refuser-doc-sentenced-for-threats-to-blow-up-hospital/ A federal jury awarded $13 million to a former employee of Blue Cross Blue Shield of Michigan who said she was fired for refusing the COVID shot. (CBS Detroit) Omar Marar, MD, who threatened to blow up a Michigan hospital, was sentenced to 6 months of probation. Marar reportedly was in […]
Surgeons Billed $2 Billion for Unnecessary Spine Surgeries: Report
Source link : https://www.newshealth.biz/health-news/surgeons-billed-2-billion-for-unnecessary-spine-surgeries-report/ More than 200,000 Medicare patients with back pain underwent $2 billion worth of unnecessary surgeries, including spinal fusion and/or laminectomy or vertebroplasty, over a recent 3-year period, according to an analysis of Medicare claims data from the Lown Institute. If unnecessary, such procedures put patients at risk of blood clots, pneumonia, […]
Infection Plus Pollution Equals Increased Alzheimer’s Risk
Source link : https://www.newshealth.biz/health-news/infection-plus-pollution-equals-increased-alzheimers-risk/ The combination of a history of infections and exposure to traffic-related air pollution increased the risk for Alzheimer’s disease (AD) by 177% in adults aged 60-75 years, based on data from approximately 100,000 individuals. A growing evidence base suggests that vulnerability to infections plays a role in the development of AD, […]
Folic acid to be added to flour to help stop birth defects
Source link : https://www.newshealth.biz/health-news/folic-acid-to-be-added-to-flour-to-help-stop-birth-defects/ Folic acid is to be added to non-wholemeal wheat flour in the UK to help prevent birth defects. Adding folic acid to flour could prevent around 200 cases of neural tube defects, such as spina bifida, every year, and improve the health of pregnant women, says the government, which is giving […]
State Medical Boards Lax When It Comes to Doctor Discipline
Source link : https://www.newshealth.biz/health-news/state-medical-boards-lax-when-it-comes-to-doctor-discipline/ State medical boards aren’t doing enough to discipline potentially dangerous doctors, according to a report from Public Citizen. On average, the rate of serious disciplinary actions such as license revocation was 0.81 per 1,000 doctors, a 12% decrease from the previous report (0.92 per 1,000 doctors), according to Robert Oshel, PhD, […]
‘Full House’ Star’s Cancer; Fluoride Fears Go Mainstream; Florida Doctor Arrested
Source link : https://www.newshealth.biz/health-news/full-house-stars-cancer-fluoride-fears-go-mainstream-florida-doctor-arrested/ Note that some links may require registration or subscription. “Full House” actor Dave Coulier, 65, revealed he has stage 3 non-Hodgkin’s lymphoma. (People) The latest tally of the McDonald’s onion E. coli outbreak reports that at least 104 were sickened and 34 hospitalized, according to the CDC. Thanks to Robert F. […]
GLP-1 Prescribing Decisions: Compounded or Brand-Name?
Source link : https://www.newshealth.biz/health-news/glp-1-prescribing-decisions-compounded-or-brand-name/ The decision to prescribe a compounded or brand-name glucagon-like peptide 1 (GLP-1) medication for obesity treatment was never simple, but recent developments have complicated it further. Both Eli Lilly and Company and Novo Nordisk have asked the US Food and Drug Administration (FDA) to place their GLP-1 medications, tirzepatide and semaglutide, […]
Risk Score Predicts GI Bleeding Among Post-PCI Patients
Source link : https://www.newshealth.biz/health-news/risk-score-predicts-gi-bleeding-among-post-pci-patients/ PHILADELPHIA — Gastrointestinal (GI) bleeding after percutaneous coronary intervention (PCI) among patients on dual antiplatelet therapy (DAPT) remains risky in terms of morbidity and mortality, but the Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy (PRECISE-DAPT) score could help predict that risk, according to a study […]
New State Law Will Restrict Health Insurers’ Use of AI
Source link : https://www.newshealth.biz/health-news/new-state-law-will-restrict-health-insurers-use-of-ai/ California is taking aim at algorithms used by insurers to make prior authorization and other coverage decisions with a new law that will put limitations on how artificial intelligence (AI)–generated formulas are employed. The state also will start requiring providers to inform consumers when patient communications are generated by AI. The […]
New Approach to Avoid Health Risks From Wildfire Smoke
Source link : https://www.newshealth.biz/health-news/new-approach-to-avoid-health-risks-from-wildfire-smoke/ Some pulmonologists and other experts are not breathing easy over projections of a potential global health crisis due to wildfires. The United Nations projects a 14% global increase in extreme fires by 2030, a 30% jump by the end of 2050, and a 50% increase by the end of the century. […]
Burden of Noninfectious Uveitis on Quality of Life
Source link : https://www.newshealth.biz/health-news/burden-of-noninfectious-uveitis-on-quality-of-life/ TOPLINE: Noninfectious uveitis (NIU) significantly affects quality of life (QOL), with both adult and pediatric patients having lower scores on measures of physical and mental health-related QOL (HRQOL) than people without the eye condition. METHODOLOGY: Researchers conducted a meta-analysis of 10 studies involving adult and pediatric patients with NIU. Data were […]
Sex Complicates Stroke Risk Scoring in AF
Source link : https://www.newshealth.biz/health-news/sex-complicates-stroke-risk-scoring-in-af/ The European Society of Cardiology (ESC) caused a stir when they recommended in their latest atrial fibrillation (AF) management guideline that gender no longer be included in the decision to initiate oral anticoagulation therapy. The move aims to level the playing field between men and women and follows a more nuanced […]
‘Baby milk prices punish those who don’t breastfeed’
Source link : https://www.newshealth.biz/health-news/baby-milk-prices-punish-those-who-dont-breastfeed/ Clare Smyrell Clare Smyrell says it feels “petty” to ban special offers on formula The high price of baby formula makes parents feel “punished” for not breastfeeding, mums and dads have told the BBC. The cost of baby milk has surged in recent years, while retailers in the UK are not […]
GPs Should Play a Role
Source link : https://www.newshealth.biz/health-news/gps-should-play-a-role/ Periodontitis is a chronic inflammatory disease that triggers a local immuno-inflammatory response, potentially leading to periodontal tissue destruction and tooth loss. Affecting 1.1 billion people worldwide, periodontitis is recognized as a significant public health issue. It is also linked to a number of other conditions, such as diabetes, cardiovascular disease, and […]
BRCA1/2 Carriers Face Higher Risk for Second Primary Cancer
Source link : https://www.newshealth.biz/health-news/brca1-2-carriers-face-higher-risk-for-second-primary-cancer/ TOPLINE: Survivors of breast cancer who carry BRCA1 or BRCA2 pathogenic variants face increased risks for second primary cancers, including contralateral breast cancer, ovarian cancer, and colorectal cancer. The 10-year cumulative risk for contralateral breast cancer, for instance, was 16% in BRCA1 carriers and 12% in BRCA2 carriers. METHODOLOGY: The risk […]
Workplace Violence Common in Urban EDs
Source link : https://www.newshealth.biz/health-news/workplace-violence-common-in-urban-eds/ TOPLINE: A new study has found that workplace violence (WPV) is common among healthcare workers in urban emergency departments (EDs), with 25% involving physical violence. Nurses and younger workers are at higher risk. METHODOLOGY: Researchers conducted a cross-sectional study over 2 months in 2023 in the ED of a large urban […]
Managing Long-Term Health Risks in Thyroid Cancer Survivors
Source link : https://www.newshealth.biz/health-news/managing-long-term-health-risks-in-thyroid-cancer-survivors/ CHICAGO — New research is illuminating the long-term health consequences faced by patients with thyroid cancer in areas related to fertility, bone health, and cardiovascular disease. According to researchers, thyroid cancer may increase the likelihood that women, but not men, are later diagnosed with infertility. Additionally, although patients with thyroid cancer […]
Semaglutide 2.4 mg Could Cut Medical Costs for Some
Source link : https://www.newshealth.biz/health-news/semaglutide-2-4-mg-could-cut-medical-costs-for-some/ SAN ANTONIO — Semaglutide 2.4 mg (Wegovy) was associated with a 22% reduction in annual medical costs in people with overweight/obesity and heart failure, new research from Novo Nordisk found. The significant year-to-year reduction of more than $6500 in total medical costs suggests that the drug “can be an attractive treatment […]
Prenatal Stress Tied to Higher Risk for Childhood Epilepsy
Source link : https://www.newshealth.biz/health-news/prenatal-stress-tied-to-higher-risk-for-childhood-epilepsy/ Persistent prenatal distress is associated with a significantly increased risk for epilepsy in offspring, a new study showed. Investigators emphasized that the risk was only slightly elevated, indicating that most infants born to mothers experiencing moderate stress will not develop epilepsy. Yuto Arai, MD The findings confirm more general reports of […]
Pharmacies vote to reduce services in first protest action
Source link : https://www.newshealth.biz/health-news/pharmacies-vote-to-reduce-services-in-first-protest-action/ MARK MARLOW/EPA-EFE/REX/Shutterstock This is the first time pharmacists have voted to take action in their history Pharmacy owners in England, Wales and Northern Ireland have voted in favour of cutting opening hours and stopping home deliveries for the first time, in a protest over government funding. The National Pharmacy Association (NPA), […]
Charity calls for prostate-cancer testing of high-risk men
Source link : https://www.newshealth.biz/health-news/charity-calls-for-prostate-cancer-testing-of-high-risk-men/ Getty Images Screening men born with a high risk of developing prostate cancer, once they reach the age of 45, makes financial sense, a cancer charity says. But Prostate Cancer Research also acknowledges more accurate tests would be needed to justify screening all men. There is no prostate-cancer screening programme in […]
Perioperative Anti-PD-1 in Soft-Tissue Sarcoma Boosts Disease-Free Survival
Source link : https://www.newshealth.biz/health-news/perioperative-anti-pd-1-in-soft-tissue-sarcoma-boosts-disease-free-survival/ Adding a PD-1 inhibitor to standard of care improved disease-free survival (DFS) in stage III soft-tissue sarcoma of the extremity, a randomized trial showed. In patients with mostly undifferentiated pleomorphic sarcomas, 2-year DFS with the addition of preoperative and postoperative pembrolizumab (Keytruda) infusions reached 67%, as compared with 52% with standard […]
Gabapentinoids Tied to Hip Fractures in Older Adults
Source link : https://www.newshealth.biz/health-news/gabapentinoids-tied-to-hip-fractures-in-older-adults/ Gabapentinoids — pregabalin and gabapentin — were tied to increased hip fracture risk in older adults. Risks were high for people with chronic kidney disease or significant frailty. Odds of hip fracture remained high after adjusting for other central nervous system medications. Gabapentinoids — gabapentin (Neurontin) and pregabalin (Lyrica) — were […]
Will Trump Adopt the Current FTC’s Antitrust Posture?
Source link : https://www.newshealth.biz/health-news/will-trump-adopt-the-current-ftcs-antitrust-posture/ The Federal Trade Commission (FTC) under Chair Lina Khan took an aggressive approach to tackling anticompetitive behavior in the healthcare space. MedPage Today asked policy experts and physicians whether a Trump administration would continue down that same path. “With respect to competition, it has actually been really heartening to see the […]
Air Pollution Tied to Preterm Birth Risk
Source link : https://www.newshealth.biz/health-news/air-pollution-tied-to-preterm-birth-risk/ Exposure to air pollution was associated with an increased risk of spontaneous preterm birth, according to a population-based cohort study of more than 400,000 births at one major California health system. Spontaneous preterm birth positively correlated with exposure to particulate matter 2.5 μm or less in diameter (PM2.5) (adjusted odds ratio […]
Targeted Combination Shows Promise in Metastatic Kidney Cancer
Source link : https://www.newshealth.biz/health-news/targeted-combination-shows-promise-in-metastatic-kidney-cancer/ LOUISVILLE, Ky. — More than half of patients with newly diagnosed metastatic kidney cancer responded to a novel drug combination, which held disease progression at bay for 2 years, a small multicenter clinical study showed. Frontline treatment with pazopanib (Votrient) plus bevacizumab (Avastin) led to an objective response rate (ORR) of […]
Are There Some Words That Doctors Should Never Use?
Source link : https://www.newshealth.biz/health-news/are-there-some-words-that-doctors-should-never-use/ Some “never-words” should not be used in conversations with seriously ill patients, according to a group warning against language that shuts down patient questions, offends, or limits decision-making. A physician may say, “Your mother needs to be intubated” or “she needs a transplant,” which can effectively shut down a patient or […]
GLP-1 Drugs Could Help People With Alcohol Use Disorder
Source link : https://www.newshealth.biz/health-news/glp-1-drugs-could-help-people-with-alcohol-use-disorder/ Some GLP-1 receptor agonists may hold promise as treatments for alcohol use disorder (AUD), a Swedish observational study suggested. Among more than 200,000 individuals with AUD, those taking semaglutide (Ozempic, Wegovy) had a 36% reduced risk for AUD-related hospitalization compared with those not taking a GLP-1 agent (adjusted hazard ratio [aHR] […]
RSV Severity, Deaths on Par With Flu and COVID
Source link : https://www.newshealth.biz/health-news/rsv-severity-deaths-on-par-with-flu-and-covid/ In the years before the introduction of respiratory syncytial virus (RSV) vaccines, the virus was linked with substantial hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths among adults, according to a cross-sectional analysis of CDC data. Adjusted analysis showed estimated RSV-associated hospitalization rates ranging from 48.9 per 100,000 adults during […]
Stroke Risk Is Changing With the Climate
Source link : https://www.newshealth.biz/health-news/stroke-risk-is-changing-with-the-climate/ The world endured its hottest summer on record in 2024, and the transition to fall brought devastation from multiple hurricanes in the U.S. The growing effects of climate change are widespread and becoming more severe. Now, new research is making it apparent that my field of neurointerventional surgery must confront the […]
Frailty Tied to Future Dementia
Source link : https://www.newshealth.biz/health-news/frailty-tied-to-future-dementia/ Frailty was tied to a higher risk of future dementia in older adults. Trajectories rose more rapidly 4 to 9 years before dementia onset. The analysis included 30,000 participants in the U.S. and U.K. Frailty — a measure of health deficits in multiple body systems — was tied to future risk […]
1 in 5 Adults Report Anxiety, Depression; New Esketamine Warning; Autism Dx Up 175%
Source link : https://www.newshealth.biz/health-news/1-in-5-adults-report-anxiety-depression-new-esketamine-warning-autism-dx-up-175/ One in five adults said they experienced any symptoms of anxiety or depression in a 2-week period, according to a 2022 CDC survey. The FDA added a warning to the label of esketamine nasal spray (Spravato), noting that long-term cognitive and memory impairments have been reported with ketamine misuse or abuse. […]
Novel Weekly Oral HIV Drug Safe in Early Trial of Healthy Volunteers
Source link : https://www.newshealth.biz/health-news/novel-weekly-oral-hiv-drug-safe-in-early-trial-of-healthy-volunteers/ Data from a phase Ia clinical trial of an oral, long-acting integrase inhibitor (GS-1720) in development for HIV demonstrated promising safety in healthy adults without HIV. The findings were presented at the recent IDWeek annual meeting in Los Angeles. In this MedPage Today video, Joseph Eron, MD, of the University of […]
U.S. Overdose Deaths Are Down, Giving Experts Hope for an Enduring Decline
Source link : https://www.newshealth.biz/health-news/u-s-overdose-deaths-are-down-giving-experts-hope-for-an-enduring-decline/ The decline in U.S. drug overdose deaths appears to have continued this year, giving experts hope the nation is seeing sustained improvement in the persistent epidemic. There were about 97,000 overdose deaths in the 12-month period that ended June 30, according to provisional CDC data released Wednesday. That’s down 14% from […]
Mounting evidence points to air pollution as a cause of eczema
Source link : https://www.newshealth.biz/health-news/mounting-evidence-points-to-air-pollution-as-a-cause-of-eczema/ Air pollution is hard to avoid, particularly for city dwellers Ron Adar/Alamy Air pollution is increasingly being linked to a raised risk of eczema, with the latest study showing a clear relationship between the exposure and the skin condition. Vehicles and power plants release pollutant particles with a diameter of 2.5 […]
Electronic Symptom Screening in Kids With Cancer Boosts Quality of Care
Source link : https://www.newshealth.biz/health-news/electronic-symptom-screening-in-kids-with-cancer-boosts-quality-of-care/ Symptom screening improved symptom scores among children with cancer compared with usual care, two randomized trials showed. Among 445 patients in one trial, the mean 8-week Symptom Screening in Pediatrics Tool (SSPedi) score (range 0-60, with higher scores indicating more bothersome symptoms) was 7.9 in patients who underwent symptom screening three […]
Alzheimer’s Researcher Placed on Leave; War on Drug Recovery; Lax Coroner Oversight
Source link : https://www.newshealth.biz/health-news/alzheimers-researcher-placed-on-leave-war-on-drug-recovery-lax-coroner-oversight/ Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Alzheimer’s Researcher Faces Scrutiny Berislav Zlokovic, MD, PhD, a prominent Alzheimer’s researcher and the head of a major neuroscience institute at the University of Southern California (USC), was placed on an indefinite […]
Hallucinogens Tied to Striking Increased Risk of SSD
Source link : https://www.newshealth.biz/health-news/hallucinogens-tied-to-striking-increased-risk-of-ssd/ Emergency department (ED) visits related to hallucinogen use are linked to a 21-fold increased risk of schizophrenia spectrum disorder (SSD), results of a large population-based study show. Daniel T. Myran, MD Results of the cohort study that included nearly a million people: Those with no history of psychosis who had an […]
Trump’s Age: Is It a Risk?
Source link : https://www.newshealth.biz/health-news/trumps-age-is-it-a-risk/ When president-elect Donald Trump is sworn in for a second term he will become the oldest president ever inaugurated — raising questions as to whether the 78-year-old is at risk of a major health event while in office. S. Jay Olshansky, PhD, of the University of Illinois Chicago, and colleagues previously […]
STI Epidemic Slows as New Syphilis and Gonorrhea Cases Fall in the U.S.
Source link : https://www.newshealth.biz/health-news/sti-epidemic-slows-as-new-syphilis-and-gonorrhea-cases-fall-in-the-u-s/ The U.S. syphilis epidemic slowed dramatically last year, gonorrhea cases fell, and chlamydia cases remained below prepandemic levels, according to federal data released Tuesday. The numbers represented some good news about sexually transmitted infections (STIs), which experienced some alarming increases in past years due to declining condom use, inadequate sex education, […]
Targeted Magnetic Stimulation Slows Alzheimer’s Progression in Phase II Study
Source link : https://www.newshealth.biz/health-news/targeted-magnetic-stimulation-slows-alzheimers-progression-in-phase-ii-study/ A personalized transcranial magnetic stimulation (TMS) protocol, designed to stimulate the precuneus within the default mode network, was well tolerated and significantly slowed clinical decline in patients with mild-to-moderate Alzheimer’s disease, according to data from a small phase II trial presented at the Clinical Trials on Alzheimer’s Disease (CTAD) annual meeting […]
Why we now think the myopia epidemic can be slowed – or even reversed
Source link : https://www.newshealth.biz/health-news/why-we-now-think-the-myopia-epidemic-can-be-slowed-or-even-reversed/ I vividly remember getting my first pair of glasses as a child. My mum is very near-sighted and dispatched me to the optician every year. My older sister was diagnosed at around the age of 8 and I prayed I wouldn’t follow suit for fear of being made fun of, but […]
Wounds in Fentanyl Users Exposed to Xylazine Described
Source link : https://www.newshealth.biz/health-news/wounds-in-fentanyl-users-exposed-to-xylazine-described/ TOPLINE: A case series highlights the features of severe, necrotic skin wounds among hospitalized adults associated with xylazine exposure, including 9% that involved exposed deep structures such as bone or tendon. METHODOLOGY: The alpha-2 agonist xylazine, a veterinary sedative, is increasingly detected in fentanyl used illicitly in the United States and […]
New Sexually Transmitted Fungal Infection Emerges in MSM
Source link : https://www.newshealth.biz/health-news/new-sexually-transmitted-fungal-infection-emerges-in-msm/ A dermatophyte known as Trichophyton mentagrophytes genotype VII (TMVII) has been identified as the cause of an emerging sexually transmitted fungal infection in four adults in the United States, according to a paper published in the Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report (MMWR). TMVII is a […]
Patients With Cushing Syndrome Face Higher Glaucoma Risk
Source link : https://www.newshealth.biz/health-news/patients-with-cushing-syndrome-face-higher-glaucoma-risk/ TOPLINE: Patients with endogenous Cushing syndrome (CS) have a higher risk for glaucoma than the general population, with the clinical manifestations appearing at a younger age. The risk persisted regardless of the remission status of CS or the degree of elevation of urinary free cortisol levels. METHODOLOGY: Researchers conducted a retrospective […]
What Docs Wish Med Students Knew
Source link : https://www.newshealth.biz/health-news/what-docs-wish-med-students-knew/ Despite 4 years of med school and 3-7 years in residency, when you enter the workforce as a doctor, you still have much to learn. There is only so much your professors and attending physicians can pack in. Going forward, you’ll continue to learn on the job and via continuing education. […]
Calif Dengue Cases Prompt Swift Public Health Response
Source link : https://www.newshealth.biz/health-news/calif-dengue-cases-prompt-swift-public-health-response/ Jason Farned and his team at the San Gabriel Valley Mosquito and Vector Control District had spent years preparing for the likely arrival of dengue, a dangerous virus typically found in tropical climates outside the mainland United States. They’d watched nervously as invasive Aedes mosquito species that can carry the virus […]
First TAVR for Aortic Regurgitation Moves to Phase 3 Trial
Source link : https://www.newshealth.biz/health-news/first-tavr-for-aortic-regurgitation-moves-to-phase-3-trial/ WASHINGTON — A phase 3 randomized trial will soon begin for the first transcatheter aortic valve replacement (TAVR) device for the treatment of aortic valve regurgitation after promising results in a 2-year initial study. If this novel option performs as well as surgical aortic valve replacement (SAVR) in the coming trial, […]
‘Nonsensical’ Limits on Support Drugs Complicate Cancer Care
Source link : https://www.newshealth.biz/health-news/nonsensical-limits-on-support-drugs-complicate-cancer-care/ A young woman with breast cancer was experiencing such intense hot flashes from her triplet chemotherapy regimen, AC-T, that she begged to stop treatment. Her oncologist, Ramy Sedhom, MD, suggested she take oxybutynin, an inexpensive drug for overactive bladder that has been shown to help reduce hot flashes. But her insurer […]
Thrombectomy Tops Thrombolysis in Pulmonary Embolism Trial
Source link : https://www.newshealth.biz/health-news/thrombectomy-tops-thrombolysis-in-pulmonary-embolism-trial/ WASHINGTON, DC — Large-bore mechanical thrombectomy is superior to catheter-directed thrombolysis for pulmonary embolism, according to a randomized trial comparing the two interventions. Although there was no difference in major events, mechanical thrombectomy had a list of advantages including faster clinical and hemodynamic improvement. The study, called PEERLESS, enrolled 550 patients […]
The Uneven Burden of Idiopathic Intracranial Hypertension in US Women
Source link : https://www.newshealth.biz/health-news/the-uneven-burden-of-idiopathic-intracranial-hypertension-in-us-women/ TOPLINE: Idiopathic intracranial hypertension (IIH) affects 3.44 per 10,000 women aged 18-55 years in the United States. Significant geographic variation in cases of the condition exists, potentially reflecting factors such as the prevalence of obesity. METHODOLOGY: Researchers conducted a retrospective cross-sectional study using data from Medicaid claims and electronic health records […]
Endoscopic Sleeve Gastroplasty Durable at 10 Years
Source link : https://www.newshealth.biz/health-news/endoscopic-sleeve-gastroplasty-durable-at-10-years/ PHILADELPHIA — New data showed durable weight loss of about 10% at 10 years after endoscopic sleeve gastroplasty (ESG) in adults with obesity. “The procedure is dependable and safe and should be considered among individuals who have not attained their desired results through lifestyle medications and those who are not eligible […]
Medical Boards Barely Acted Amid Flood of COVID Misinformation
Source link : https://www.newshealth.biz/health-news/medical-boards-barely-acted-amid-flood-of-covid-misinformation/ Only a handful of physicians in the five most populous states faced medical board discipline over spreading misinformation to the community during the height of the COVID-19 pandemic, a new study found. In California, Texas, Florida, New York, and Pennsylvania, only six physicians were disciplined for disseminating medical misinformation in the […]
Weight Loss Treatments Beyond the Reach of Many in Need
Source link : https://www.newshealth.biz/health-news/weight-loss-treatments-beyond-the-reach-of-many-in-need/ SAN ANTONIO — Weight loss treatments aren’t reaching many of the people who need them most due to coverage barriers, new data suggested. Findings from three studies presented on November 5 at The Obesity Society’s Obesity Week 2024 meeting illustrate different aspects of the problem. One, presented by Alissa S. Chen, […]
Alcohol Use Disorder Therapy Remains Underutilized in ALD
Source link : https://www.newshealth.biz/health-news/alcohol-use-disorder-therapy-remains-underutilized-in-ald/ PHILADELPHIA — Patients with alcohol-associated liver disease (ALD) could benefit from treatment of alcohol use disorder (AUD), yet pharmacologic therapy remains underutilized in this at-risk group, according to a study presented at the American College of Gastroenterology (ACG) 2024 Annual Scientific Meeting. In an analysis of commercially insured Americans, AUD medications […]
Can Atrial Arrhythmias Predict Strokes?
Source link : https://www.newshealth.biz/health-news/can-atrial-arrhythmias-predict-strokes/ TOPLINE: Atrial arrhythmias were found in 26% of patients with sickle cell disease (SCD), with a significant association with stroke history. Early detection and treatment of atrial arrhythmias may help prevent strokes in this population. METHODOLOGY: A total of 130 adult patients with SCD were included in the DREPACOEUR prospective registry […]
When and How to Intervene
Source link : https://www.newshealth.biz/health-news/when-and-how-to-intervene/ For patients with edematous hemorrhoidal thrombosis, the first line of treatment is a nonsteroidal anti-inflammatory drug (NSAID) such as ketoprofen, in conjunction with an analgesic, as outlined by Vincent de Parades, MD, PhD, of Hôpital Paris Saint-Joseph, Paris. In his presentation at France’s annual general medicine conference (JNMG 2024) on the […]
Researchers Identify Why Some Don’t Respond to Drugs for AMD
Source link : https://www.newshealth.biz/health-news/researchers-identify-why-some-dont-respond-to-drugs-for-amd/ Researchers at Johns Hopkins University have identified a process in the eye that may explain why biologic drugs for treating age-related macular degeneration (AMD) fail in some patients. Using that new knowledge, they developed a new drug that may counteract the interference and boost the effectiveness of those treatments. The researchers, […]
Less Fatigue in Multiple Sclerosis With CBT and Modafinil
Source link : https://www.newshealth.biz/health-news/less-fatigue-in-multiple-sclerosis-with-cbt-and-modafinil/ TOPLINE: Fatigue related to multiple sclerosis (MS) was significantly reduced following 12 weeks of treatment with cognitive behavioral therapy (CBT) and modafinil, either alone or in combination, a new study shows. METHODOLOGY: Intent-to-treat analysis from the randomized, analyst-blinded, parallel-arm trial included 312 adults with MS and problematic fatigue (76% women; 85% […]
‘No Hint of Benefit’ in Large Colchicine Trial
Source link : https://www.newshealth.biz/health-news/no-hint-of-benefit-in-large-colchicine-trial/ WASHINGTON — Colchicine does not protect against major cardiovascular adverse events after an acute myocardial infarction, according to a multinational placebo-controlled trial of more than 7000 patients. The CLEAR SYNERGY (OASIS 9) study, called “the largest trial ever of colchicine in acute MI,” showed no hint of benefit in an adverse […]
Fashion industry ‘should be concerned’ by return to skinny models, Vogue boss Chioma Nnadi says
Source link : https://www.newshealth.biz/health-news/fashion-industry-should-be-concerned-by-return-to-skinny-models-vogue-boss-chioma-nnadi-says/ The fashion industry “should be concerned” by a trend back to using more skinny models, the editorial director of British Vogue has said. Chioma Nnadi suggested the change, following recent progress in body diversity, had been partly fuelled by the rise in popularity of weight-loss drugs. “I do think maybe perhaps […]
From Primary Care to Specialization
Source link : https://www.newshealth.biz/health-news/from-primary-care-to-specialization/ Physician assistants (PAs) are educated as generalists — with the ability to switch medical specialties during their career. Andrzej Kozikowski, PhD, senior director of research at the National Commission on Certification of Physician Assistants (NCCPA), said that having that kind of career flexibility is often a motivating factor for students who […]